Nutritional Supplement

Vanadium

Possible Deficiencies

Deficiencies of vanadium have not been reported in humans, and it is not known whether this mineral is essential for humans.

Side Effects

Information about vanadium toxicity is limited. Workers exposed to vanadium dust can develop toxic effects. High blood levels have been linked to manic-depressive mental disorders, but the meaning of this remains uncertain.7 Vanadium sometimes inhibits, but at other times stimulates, cancer growth in animals. However, the effect in humans remains unknown.8

References

1. Cohen N, Halberstam M, Shlimovich P, et al. Oral vanadyl sulfate improves hepatic and peripheral insulin sensitivity in patients with non-insulin-dependent diabetes mellitus. J Clin Invest 1995;95:2501–9.

2. Boden G, Chen X, Ruiz J, et al. Effects of vanadyl sulfate on carbohydrate and lipid metabolism in patients with non-insulin dependent diabetes mellitus. Metabolism 1996;45:1130–5.

3. Cusi K, Cukier S, DeFronzo R, et al. Vanadyl sulfate improves hepatic and muscle insulin sensitivity in type 2 diabetes. J Clin Endocrinol Metab 2001;86:1410–7.

4. Halberstam M, Cohen N, Schlimovich P, et al. Oral vanadyl sulfate improves insulin sensitivity in NIDDM but not in obese nondiabetic subjects. Diabetes 1996;45:659–66.

5. Goldfine A, Patti M, Zuberi L, et al. Metabolic effects of vanadyl sulfate in humans with non-insulin-dependent diabetes mellitus: in vivo and in vitro studies. Metabolism 2000;49:400–10.

6. Thompson K, Lichter J, LeBel C, et al. Vanadium treatment of type 2 diabetes: a view to the future. J Inorg Biochem 2009;103:554–8.

7. Naylor GJ. Vanadium and manic depressive psychosis. Nutr Health 1984;3:79-85 [review].

8. Chakraborty A, Ghosh R, Roy K, et al. Vanadium: a modifier of drug metabolizing enzyme patterns and its critical role in cellular proliferation in transplantable murine lymphoma. Oncology 1995;52:310-4.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.