Nutritional Supplement

Tea Tree

Side Effects

While tea tree oil can be applied to minor cuts and scrapes, use caution for more extensive areas of broken skin or areas affected by rashes not due to fungus. The oil may burn if it gets into the eyes, nose, mouth, or other tender areas. Some people have allergic reactions, including rashes and itching, when applying tea tree oil.26 For this reason, only a small amount should be applied when first using it.

In case reports, three young boys developed breast enlargement (gynecomastia) after repeated topical application of products that contained lavender oil and tea tree oil. The problem resolved after they stopped using the oils. While a cause–effect relationship was not conclusively proven, it was suggested by the fact that these oils have been found to have estrogen-like effects in test tube studies.27 Tea tree oil should never be swallowed, as it may cause nerve damage and other problems.

References

1. Carson CF, Riley TV. Antimicrobial activity of the essential oil of Melaleuca alternifolia: A review. Lett Appl Microbiol 1993;16:49-55.

2. Carson CF, Cookson BD, Farrelly HD, Riley T. Susceptibility of methicillin-resistant Staphylococcus aureus to the essential oil of Melaleuca alternifolia. J Antimicrobial Chemother 1995;35:421-4.

3. Bassett IB, Pannowitz DL, Barnetson RS. A comparative study of tea-tree oil versus benzoylperoxide in the treatment of acne. Med J Austral 1990;153:455-8.

4. Tong MM, Altman PM, Barnetson RS. Tea tree oil in the treatment of tinea pedis. Austral J Dermatol 1992;33:145-9.

5. Buck DS, Nidorf DM, Addino JG. Comparison of two topical preparations for the treatment of onychomycosis: Melaleuca alternifolia (tea tree) oil and clotrimazole. J Fam Pract 1994;38:601-5.

6. Syed TA, Qureshi ZA, Ali SM, et al. Treatment of toenail onychomycosis with 2% butenafine and 5% Melaleuca alternifolia (tea tree) oil in cream. Trop Med Intl Health 1999;4:284-7.

7. Jandourek A, Vaishampayan JK, Vazquez JA. Efficacy of melaleuca oral solution for the treatment of fluconazole refractory oral candidiasis in AIDS patients. AIDS 1998;12:1033-7.

8. Caelli M, Porteous J, Carson CF, et al. Tea tree oil as an alternative topical decolonization agent for methicillin-resistant Staphylococcus aureus. J Hospital Infect 2000;46:236-7.

9. Enshaieh S, Jooya A, Siadat AH, Iraji F. The efficacy of 5% topical tea tree oil gel in mild to moderate acne vulgaris: a randomized, double-blind placebo-controlled study. Indian J Dermatol Venereol Leprol 2007;73:22-5.

10. Tong MM, Altman PM, Barnetson RS. Tea tree oil in the treatment of tinea pedis. Austral J Dermatol 1992;33:145-9.

11. Carson CF, Riley TV. Antimicrobial activity of the essential oil of Melaleuca alternifolia: A review. Lett Appl Microbiol 1993;16:49-55.

12. Faoagali J, George N, Leditschke JF. Does tea tree oil have a place in the topical treatment of burns? Burns 1997;23:349-51.

13. Jandourek A, Vaishampayan JK, Vazquez JA. Efficacy of melaleuca oral solution for the treatment of fluconazole refractory oral candidiasis in AIDS patients. AIDS 1998;12:1033-7.

14. Kato T, Iijima H, Ishihara K, et al. Antibacterial effects of Listerine on oral bacteria. Bull Tokyo Dent Coll 1990;31:301-7.

15. Cosentino S, Tuberoso CI, Pisano B, et al. In-vitro antimicrobial activity and chemical composition of Sardinian Thymus essential oils. Lett Appl Microbiol 1999;29:130-5.

16. Petersson LG, Edwardsson S, Arends J. Antimicrobial effect of a dental varnish, in vitro. Swed Dent J 1992;16:183-9.

17. Cox SD, Mann CM, Markham JL, et al. The mode of antimicrobial action of the essential oil of Melaleuca alternifolia (tea tree oil). J Appl Microbiol 2000;88:170-5.

18. Serfaty R, Itic J. Comparative trial with natural herbal mouthwash versus chlorhexidine in gingivitis. J Clin Dent 1988;1:A34-7.

19. Dolara P, Corte B, Ghelardini C, et al. Local anaesthetic, antibacterial and antifungal properties of sesquiterpenes from myrrh. Planta Med 2000;66:356-8.

20. Hannah JJ, Johnson JD, Kuftinec MM. Long-term clinical evaluation of toothpaste and oral rinse containing sanguinaria extract in controlling plaque, gingival inflammation, and sulcular bleeding during orthodontic treatment. Am J Orthod Dentofacial Orthop 1989;96:199-207.

21. Carson CF, Riley TV. Antimicrobial activity of the essential oil of Melaleuca alternifolia: A review. Lett Appl Microbiol 1993;16:49-55.

22. Faoagali J, George N, Leditschke JF. Does tea tree oil have a place in the topical treatment of burns? Burns 1997;23:349-51.

23. Jandourek A, Vaishampayan JK, Vazquez JA. Efficacy of melaleuca oral solution for the treatment of fluconazole refractory oral candidiasis in AIDS patients. AIDS 1998;12:1033-7.

24. Pena E. Melaleuca alternifolia oil: Its use for trichomonal vaginitis and other vaginal infections. Obstet Gynecol 1962;19:793-5.

25. Brown DJ. Phytotherapeutic approaches to common dermatological conditions. Quart Rev Natural Med 1998;Summer:161-73.

26. Knight TE, Hansen BM. Melaleuca oil (tea tree oil) dermatitis. Med J Australia 1994;30:423-7.

27. Henley DV, Lipson N, Korach KS, Bloch CA. Prepubertal gynecomastia linked to lavender and tea tree oils. N Engl J Med 2007;356:479-85.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.