Nutritional Supplement

Taurine

  • Heart and Circulatory Health

    Hypertension

    Taurine supplementation has been found to result in small reductions in both systolic and diastolic blood pressures.
    Hypertension
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    Taurine is a semi-essential amino acid (one that can be made in the body but not in sufficient quantity) that is especially important to normal heart and brain function. Its cardiovascular benefits may be related to its antioxidant properties, its role in regulating calcium flow across cell membranes, and its ability to relax blood vessels by increasing nitric oxide production.1,2 In a placebo-controlled trial, 120 subjects with pre-hypertension were given either 1.6 grams of taurine daily or placebo for 12 weeks; those who received taurine had an average 4.6 mmHg greater drop in systolic blood pressure and 3.3 mmHg drop in diastolic blood pressure.3 A meta-analysis pooled data from seven trials with a combined total of 103 participants and concluded taurine can effectively reduce both systolic and diastolic blood pressures by an average of 3 mmHg when used in doses between 1 and 6 grams per day for up to 12 weeks.4

    Congestive Heart Failure

    Taurine, an amino acid, helps increase the force and effectiveness of heart muscle contractions.
    Congestive Heart Failure
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    Taurine, an amino acid, helps increase the force and effectiveness of heart-muscle contractions. Research (some double-blind) has shown that taurine helps people with CHF.5,6,7,8 Most doctors suggest taking 2 grams three times per day.

    Cardiomyopathy

    Taurine has been shown in preliminary studies to be beneficial for cardiomyopathy.
    Cardiomyopathy
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    Several veterinary studies have demonstrated benefits from supplementation with taurine, another amino acid, in animals with cardiomyopathy. Most of these studies showed taurine deficiency to be a cause of cardiomyopathy. Taurine supplementation in animals with DCM has resulted in improvement of symptoms and survival rates.9,10 However, clinical studies in humans are lacking; thus, despite a good safety record, the benefits of taurine supplementation in people with any form of cardiomyopathy remain speculative. When taurine supplements are used by doctors to treat people with other conditions, 2 grams taken three times per day for a total of 6 grams per day is often recommended.

  • Immune System Support

    Pre- and Post-Surgery Health

    Taurine is an amino acid that appears to have an important role in immune cell functions. Supplementing with it may reduce inflammation.
    Pre- and Post-Surgery Health
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    Taurine is an amino acid abundantly present in the body that also appears to have an important role in immune cell functions.11 A preliminary trial found that patients receiving an oral formula enriched with taurine (1 gram per liter) beginning two days before surgery and continuing until five days after surgery had less inflammation after surgery compared with those receiving a standard formula.12

  • Blood Sugar and Diabetes Support

    Type 1 Diabetes

    Supplementing with taurine has been found to improve blood vessel function in people with type 1 diabetes.
    Type 1 Diabetes
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    Taurine is an amino acid that is not used in protein synthesis but serves other functions in the body. Because of its role in cardiovascular and nervous system health, it may be an important nutrient for people with type 1 diabetes.13 A small crossover trial with nine young men with type 1 diabetes found, compared to placebo, supplementing with 500 mg taurine three times per day for two weeks reduced arterial stiffness and increased the blood vessel dilation response to higher blood flow, indicating taurine improved their vascular function.14 Findings from animal studies suggest taurine supplementation may improve heart and blood vessel dysfunction associated with type 1 diabetes.15,16 Evidence from laboratory studies also suggests taurine may prevent or reverse damage to insulin-producing pancreatic cells.17 Taurine also reduced diabetes-related penile muscle scarring and erectile dysfunction in a rat model of type 1 diabetes.18,19

    Type 2 Diabetes

    Supplementing with taurine may affect insulin secretion and action and may help some people with type 2 diabetes.
    Type 2 Diabetes
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    Taurine is an amino acid that affects glucose and lipid metabolism by acting as an antioxidant and participating in regulation of insulin secretion and action.20 Low taurine levels have been linked to type 2 diabetes and other metabolic disorders, and animal studies suggest taurine supplementation may protect against diabetes complications.21,22 Few studies of taurine supplementation in people with type 2 diabetes have been performed, and these have yielded mixed results; one clinical trial indicated the effects of taurine on metabolism may be determined partly by genetics.23
  • Menstrual and PMS Support

    Iron-Deficiency Anemia

    Taurine has been shown to improve the response to iron therapy in young women with iron-deficiency anemia.
    Iron-Deficiency Anemia
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    Taurine has been shown, in a double-blind study, to improve the response to iron therapy in young women with iron-deficiency anemia.24 The amount of taurine used was 1,000 mg per day for 20 weeks, given in addition to iron therapy, but at a different time of the day. The mechanism by which taurine improves iron utilization is not known.

  • Women's Health

    Iron-Deficiency Anemia

    Taurine has been shown to improve the response to iron therapy in young women with iron-deficiency anemia.
    Iron-Deficiency Anemia
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    Taurine has been shown, in a double-blind study, to improve the response to iron therapy in young women with iron-deficiency anemia.25 The amount of taurine used was 1,000 mg per day for 20 weeks, given in addition to iron therapy, but at a different time of the day. The mechanism by which taurine improves iron utilization is not known.

What Are Star Ratings?
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Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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References

1. Bkaily G, Jazzar A, Normand A, et al. Taurine and cardiac disease: state of the art and perspectives. Can J Physiol Pharmacol 2020;98:67–73.

2. Guizoni DM, Vettorazzi JF, Carneiro EM, et al. Modulation of endothelium-derived nitric oxide production and activity by taurine and taurine-conjugated bile acids. Nitric Oxide 2020;94:48–53.

3. Sun Q, Wang B, Li Y, et al. Taurine Supplementation Lowers Blood Pressure and Improves Vascular Function in Prehypertension: Randomized, Double-Blind, Placebo-Controlled Study. Hypertension 2016;67:541–9.

4. Waldron M, Patterson SD, Tallent J, et al. The Effects of Oral Taurine on Resting Blood Pressure in Humans: a Meta-Analysis.Curr Hypertens Rep 2018;20:81.

5. Azuma J, Sawamura A, Awata N, et al. Double-blind randomized crossover trial of taurine in congestive heart failure. Curr Ther Res 1983;34(4):543-57.

6. Azuma J, Hasegawa H, Sawamura N, et al. Taurine for treatment of congestive heart failure. Int J Cardiol 1982;2:303-4.

7. Azuma J, Hasegawa H, Sawamura A, et al. Therapy of congestive heart failure with orally administered taurine. Clin Ther 1983;5(4):398-408.

8. Azuma J, Takihara K, Awata N, et al. Taurine and failing heart: experimental and clinical aspects. Prog Clin Biol Res 1985;179:195-213.

9. Kittleson MD, Keene B, Pion PD, Loyer CG. Results of the multicenter spaniel trial (MUST): taurine- and carnitine-responsive dilated cardiomyopathy in American cocker spaniels with decreased plasma taurine concentration. J Vet Intern Med 1997;11:204-11.

10. Pion PD, Kittleson MD, Thomas WP, et al. Response of cats with dilated cardiomyopathy to taurine supplementation. J Am Vet Med Assoc 1992;201:275-84.

11. Redmond HP, Stapleton PP, Neary P, Bouchier-Hayes D. Immunonutrition: the role of taurine. Nutrition 1998;14:599-604 [review].

12. O'Flaherty L, Bouchier-Hayes DJ. Immunonutrition and surgical practice. Proc Nutr Soc 1999;58:831-7 [review].

13. Sirdah M. Protective and therapeutic effectiveness of taurine in diabetes mellitus: a rationale for antioxidant supplementation. Diabetes Metab Syndr 2015;9:55–64.

14. Moloney M, Casey R, O'Donnell D, et al. Two weeks taurine supplementation reverses endothelial dysfunction in young male type 1 diabetics. Diab Vasc Dis Res 2010;7:300–10.

15. Wang G, Li W, Lu X, et al. Taurine attenuates oxidative stress and alleviates cardiac failure in type I diabetic rats. Croat Med J 2013;54:171–9.

16. Wang L, Yu Y, Zhang L, et al. Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: correlated with downregulation of LOX-1 and ICAM-1 expression on aortas. Eur J Pharmacol 2008;597:75–80.

17. Gavrovskaya L, Ryzhova O, Safonova A, et al. Protective effect of taurine on rats with experimental insulin-dependent diabetes mellitus. Bull Exp Biol Med 2008;146:226–8.

18. Ruan Y, Li M, Wang T, et al. Taurine Supplementation Improves Erectile Function in Rats with Streptozotocin-induced Type 1 Diabetes via Amelioration of Penile Fibrosis and Endothelial Dysfunction. J Sex Med 2016;13:778–85.

19. Arany E, Strutt B, Romanus P, et al. Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice. Diabetologia 2004;47:1831–7.

20. Ribeiro R, Bonfleur M, Batista T, et al. Regulation of glucose and lipid metabolism by the pancreatic and extra-pancreatic actions of taurine. Amino Acids 2018;50:1511–24.

21. Sak D, Erdenen F, Muderrisoglu C, et al. The Relationship between Plasma Taurine Levels and Diabetic Complications in Patients with Type 2 Diabetes Mellitus. Biomolecules 2019;9.

22. Sarkar P, Basak P, Ghosh S, et al. Prophylactic role of taurine and its derivatives against diabetes mellitus and its related complications. Food Chem Toxicol 2017;110:109–21.

23. Zheng Y, Ceglarek U, Huang T, et al. Plasma Taurine, Diabetes Genetic Predisposition, and Changes of Insulin Sensitivity in Response to Weight-Loss Diets. J Clin Endocrinol Metab 2016;101:3820–6.

24. Sirdah MM, El-Agouza IMA, Abu Shahla ANK. Possible ameliorative effect of taurine in the treatment of iron-deficiency anaemia in female university students of Gaza, Palestine. Eur J Haematol 2002;69:236-2.

25. Sirdah MM, El-Agouza IMA, Abu Shahla ANK. Possible ameliorative effect of taurine in the treatment of iron-deficiency anaemia in female university students of Gaza, Palestine. Eur J Haematol 2002;69:236-2.

26. Franconi F, Bennardini F, Mattana A, et al. Plasma and platelet taurine are reduced in subjects with insulin-dependent diabetes mellitus: effects of taurine supplementation. Am J Clin Nutr 1995;61:1115-9.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.