Nutritional Supplement

Methylsulfonylmethane

Where to Find It

A precursor of MSM is formed initially by ocean plankton and released into the atmosphere, where it interacts with ozone and sunlight and returns to earth as MSM in rainfall. MSM can be taken up by plants and incorporated into their structure, but no measurement of the MSM content of foods has been done. Supplements containing MSM are available.

How to Use It

Some authorities report anecdotally that 250–500 mg per day has beneficial effects on a variety of health problems.4 However, the only controlled trial using MSM used over 2000 mg per day to treat osteoarthritis. More research is needed before reliable recommendations for MSM supplementation can be made.

References

1. Jacob SW, Herschler R. Dimethyl sulfoxide after twenty years. Ann N Y Acad Sci. 1983;411:xiii-xvii.

2. Lawrence RM. Methylsulfonylmethane (MSM): a double-blind study of its use in degenerative arthritis. Int J of Anti-Aging Med 1998;1:50.

3. Kim LS, Axelrod LJ, Howard P, et al. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage 2006;14:286-94.

4. Jacob SW, Herschler R. Dimethyl sulfoxide after twenty years. Ann N Y Acad Sci. 1983;411:xiii-xvii.

5. Jacob SW. Oregon Health Sciences University, Portland, Oregon. Unpublished communication.

6. Rose SE, Chalk JB, Galloway GJ, Doddrell DM. Detection of dimethyl sulfone in the human brain by in vivo proton magnetic resonance spectroscopy. Magn Reson Imaging 2000;18:95-8.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.