Nutritional Supplement

Medium-Chain Triglycerides

  • Fitness

    Athletic Performance

    Medium-chain triglycerides contain a class of fatty acids that are more rapidly absorbed and burned as energy than other fats. For this reason, athletes have been interested in their use, especially during prolonged endurance exercise.
    Athletic Performance
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    Medium chain triglycerides (MCT) contain a class of fatty acids found only in very small amounts in the diet; they are more rapidly absorbed and burned as energy than are other fats.3 For this reason, athletes have been interested in their use, especially during prolonged endurance exercise. However, no effect on carbohydrate sparing or endurance exercise performance has been shown with moderate amounts of MCT (30 to 45 grams over two to three hours).4,5 Controlled trials using very large amounts of MCT (approximately 85 grams over two hours) have resulted in both increased and decreased performance,6,7 while a double-blind trial found that 60 grams per day of MCT for two weeks had no effect on endurance performance.8 A controlled study found increased performance when MCTs were added to a 10% carbohydrate solution,6 but another study found no advantage of adding MCT,10 and a third trial actually reported decreased performance with this combination, probably due to gastrointestinal distress, in athletes using MCTs.7
  • Blood Sugar and Diabetes Support

    Type 2 Diabetes

    Replacing other dietary fats with medium-chain triglycerides may lead to metabolic benefits in people with type 2 diabetes.
    Type 2 Diabetes
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    Medium-chain triglycerides (MCT) contain fatty acids that have six to twelve carbon units and are found mainly in coconut and palm oils. Studies in which people with type 2 diabetes replaced usual long-chain fatty acid sources with MCT oils indicate its potential benefits. In a pilot trial, getting 31% of per day calories from MCTs for five days led to reduced post-meal blood glucose levels and appeared to strengthen insulin sensitivity in people with type 2 diabetes.10 Other preliminary research noted 30 days of getting 18% of per day calories from MCTs led to slight improvement in post-meal blood glucose control but no other measurable changes in glucose metabolism.11 A controlled trial found moderately overweight people with type 2 diabetes who took 18 grams per day of MCTs for 90 days had decreased insulin resistance, greater weight loss, and more reduction in waist circumference than those who took long-chain triglycerides.12
What Are Star Ratings?
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Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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References

1. Bach AC, Ingenbleek Y, Frey A. The usefulness of dietary medium-chain triglycerides in body weight control: fact or fancy? J Lipid Res 1996;37:708-26.

2. Bach AC, Babayan VK. Medium-chain triglycerides—an update. Am J Clin Nutr 1982;36:950-62.

3. Jeukendrup AE, Saris WHM, van Diesen RAJ, et al. Exogenous MCT oxidation from carbohydrate-medium chain triglyceride supplements during moderate intensity exercise. Clin Sci 1994;87:33.

4. Berning JR. The role of medium-chain triglycerides in exercise. Int J Sport Nutr 1996;6:121-33 [review].

5. Goedecke JH, Elmer-English R, Dennis SC, et al. Effects of medium-chain triaclyglycerol ingested with carbohydrate on metabolism and exercise performance. Int J Sport Nutr 1999;9:35-47.

6. Van Zyl CG, Lambert EV, Hawley JA, et al. Effects of medium-chain triglyceride ingestion on carbohydrate metabolism and cycling performance. J Appl Physiol 1996;80:2217-25.

7. Jeukendrup AE, Thielen JJ, Wagenmakers AJ, et al. Effect of medium-chain triacylglycerol and carbohydrate ingestion during exercise on substrate utilization and subsequent cycling performance. Am J Clin Nutr 1998;67:397-404.

8. Misell LM, Lagomarcino ND, Schuster V, Kern M. Chronic medium-chain triacylglycerol consumption and endurance performance in trained runners. J Sports Med Phys Fitness 2001;41:210-5.

9. Angus DJ, Hargreaves M, Dancey J, Febbraio MA. Effect of carbohydrate or carbohydrate plus medium-chain triglyceride ingestion on cycling time trial performance. J Appl Physiol 2000;88:113-9.

10. Eckel R, Hanson A, Chen A, et al. Dietary substitution of medium-chain triglycerides improves insulin-mediated glucose metabolism in NIDDM subjects. Diabetes 1992;41:641–7.

11. Yost T, Erskine J, Gregg T, et al. Dietary substitution of medium chain triglycerides in subjects with non-insulin-dependent diabetes mellitus in an ambulatory setting: impact on glycemic control and insulin-mediated glucose metabolism. J Am Coll Nutr 1994;13:615–22.

12. Han J, Deng B, Sun J, et al. Effects of dietary medium-chain triglyceride on weight loss and insulin sensitivity in a group of moderately overweight free-living type 2 diabetic Chinese subjects. Metabolism 2007;56:985–91.

13. Cater NB, Heller HJ, Denke MA. Comparison of the effects of medium-chain triacylglycerols, palm oil, and high oleic acid sunflower oil on plasma triacylglycerol fatty acids and lipid and lipoprotein concentrations in humans. Am J Clin Nutr 1997;65:41-5.

14. Hill JO, Peters JC, Swift LL, et al. Changes in blood lipids during six days of overfeeding with medium or long chain triglycerides. J Lipid Res 1990;31:407-16.

15. Fan ST. Review: nutritional support for patients with cirrhosis. J Gastroenterol Hepatol 1997;12:282-6.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.