Nutritional Supplement

Green Coffee Extract for Weight Control

Coffee

How to Use It

Green coffee extracts are typically standardized to contain 50% chlorogenic acids. Amounts of green coffee extracts that provide from 140 to 480 mg chlorogenic acids daily are usually taken.

References

1. Alonso-Salces RM, Serra F, Reniero F, Héberger K. Botanical and geographical characterization of green coffee (Coffea arabica and Coffea canephora): chemometric evaluation of phenolic and methylxanthine contents. J Agric Food Chem 2009;57:4224-35.

2. Farah A, Monteiro M, Donangelo CM, Lafay S. Chlorogenic acids from green coffee extract are highly bioavailable in humans. J Nutr 2008;138:2309-15.

3. Iwai K, Kishimoto N, Kakino Y, et al. In vitro antioxidative effects and tyrosinase inhibitory activities of seven hydroxycinnamoyl derivatives in green coffee beans. J Agric Food Chem 2004;52:4893-8.

4. Glei M, Kirmse A, Habermann N, et al. Bread enriched with green coffee extract has chemoprotective and antigenotoxic activities in human cells. Nutr Cancer 2006;56:182-92.

5. Del Rio D, Stalmach A, Calani L, Crozier A. Bioavailability of coffee chlorogenic acids and green tea flavan-3-ols. Nutrients 2010;2:820-33 [review].

6. Ochiai R, Jokura H, Suzuki A, et al. Green coffee bean extract improves human vasoreactivity. Hypertens Res 2004;27:731-7.

7. Zhao Y, Wang J, Ballevre O, et al. Antihypertensive effects and mechanisms of chlorogenic acids. Hypertens Res 2012;35:370-4 [review].

8. Cho AS, Jeon SM, Kim MJ, et al. Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice. Food Chem Toxicol 2010;48:937-43.

9. Yamaguchi T, Chikama A, Mori K, et al. Hydroxyhydroquinone-free coffee: a double-blind, randomized controlled dose-response study of blood pressure. Nutr Metab Cardiovasc Dis 2008;18:408-14.

10. de Melo Pereira GV, de Carvalho Neto DP, Magalhães Júnior AI, et al. Chemical composition and health properties of coffee and coffee by-products. Advances in Food and Nutrition Research. 2020;91:65-96

11. Tian T, Freeman S, Corey M, et al. Chemical characterization of potentially prebiotic oligosaccharides in brewed coffee and spent coffee grounds. Journal of Agricultural and Food Chemistry. 2017 Apr;65(13):2784-2792.

12. Mills CE, Tzounis X, Oruna-Concha MJ, et al. In vitro colonic metabolism of coffee and chlorogenic acid results in selective changes in human faecal microbiota growth. The British Journal of Nutrition. 2015 Apr;113(8):1220-7.

13. Poole R, Kennedy OJ, Roderick P, et al. Coffee consumption and health: umbrella review of meta-analyses of multiple health outcomes. BMJ (Clinical research ed.). 2017 11;359:j5024.

14. Gorji Z, Varkaneh HK, Talaei S, et al. The effect of green-coffee extract supplementation on obesity: A systematic review and dose-response meta-analysis of randomized controlled trials. Phytomedicine 2019 Oct;63:153018.

15. Asbaghi O, Sadeghian M, Rahmani S, et al. The effect of green coffee extract supplementation on anthropometric measures in adults: A comprehensive systematic review and dose-response meta-analysis of randomized clinical trials. Complementary Therapies in Medicine. 2020 Jun;51:102424.

16. Naveed M,Hejazi V, Abbas M, et al. Chlorogenic acid (CGA): A pharmacological review and call for further research. Biomed Pharmacother 2018;97:67–74.

17. Pimpley V, Patil S,Srinivasan K, et al. The chemistry of chlorogenic acid from green coffee and its role in attenuation of obesity and diabetes. Prep Biochem Biotechnol 2020;50:969–78.

18. Han B, Nazary-Vannani A, Talaei S, et al. The effect of green coffee extract supplementation on blood pressure: A systematic review and meta-analysis of randomized controlled trials. Phytother Res 2019 Nov;33:2918–26.

19. Reis C, Dorea J, da Costa T. Effects of coffee consumption on glucose metabolism: A systematic review of clinical trials. J Tradit Complement Med 2019;9:184–91.

20. Rebelo I, Casal S. Coffee: A Dietary Intervention on Type 2 Diabetes? Curr Med Chem 2017;24:376–83.

21. Tunnicliffe J, Shearer J. Coffee, glucose homeostasis, and insulin resistance: physiological mechanisms and mediators. Appl Physiol Nutr Metab 2008;33:1290–300.

22. Henry-Vitrac C, Ibarra A, Roller M. Contribution of chlorogenic acids to the inhibition of human hepatic glucose-6-phosphatase activity in vitro by Svetol, a standardized decaffeinated green coffee extract. J Agric Food Chem 2010;58:4141–4.

23. Ho L, Varghese M, Wang J, et al. Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice. Nutr Neurosci 2012;15:37–45.

24. Thom E. The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people J Int Med Res 2007;35:900–8.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.