Nutritional Supplement

Ginger

  • Digestive Support

    Morning Sickness

    Ginger, well-known for alleviating nausea and improving digestion, appears to be an effective and safe treatment for nausea and vomiting in pregnancy.
    Morning Sickness
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    Ginger is well-known for alleviating nausea and improving digestion. One gram of encapsulated ginger powder was used in one study to reduce the severe nausea and vomiting associated with hyperemesis gravidarum.18 This condition is potentially life-threatening and should only be treated by a qualified healthcare professional. A review of six double-blind trials concluded that ginger is probably an effective treatment for nausea and vomiting in pregnancy.19

    Because ginger contains some compounds that cause chromosomal mutation in the test tube, some doctors are concerned about the safety of using ginger during pregnancy. However, the available clinical research, combined with the fact that ginger is widely used in the diets of many cultures, suggests that prudent use of ginger for morning sickness is probably safe in amounts up to 1 gram per day.20

    Motion Sickness

    Ginger may help prevent and treat mild to moderate cases of motion sickness. Studies have shown it to be as effective as dimenhydrinate (Dramamine) but with fewer side effects.
    Motion Sickness
    ×

    Ginger may be useful for the prevention and treatment of mild to moderate cases of motion sickness. A double-blind trial examined the effects of ginger supplements in people who were susceptible to motion sickness. Researchers found that those taking 940 mg of powdered ginger in capsules experienced less motion sickness than those who took dimenhydrinate (Dramamine).21 Another double-blind trial reported that 1 gram of powdered ginger root, compared with placebo, lessened seasickness by 38% and vomiting by 72% in a group of naval cadets sailing in heavy seas.22 Two clinical trials, one with adults and one with children, found that ginger was as effective in treating seasickness as dimenhydrinate but with fewer side effects.23,24 In one controlled trial, though, neither powdered ginger (500 to 1,000 mg) nor fresh ginger (1,000 mg) provided any protection against motion sickness.25 Doctors prescribing ginger for motion sickness recommend 500 mg one hour before travel and then 500 mg every two to four hours as necessary. The study with children used one-half the adult amount.

    Ginger’s beneficial effect on motion sickness appears to be related to its action on the gastrointestinal tract rather than on the central nervous system.26,27

    Indigestion, Heartburn, and Low Stomach Acidity

    Ginger, with its anti-inflammatory and anti-nausea effects, has a history of use in treating gastrointestinal complaints, from flatulence to ulcers. It has been shown to enhance intestinal movements that aid digestion.
    Indigestion, Heartburn, and Low Stomach Acidity
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    Carminatives (also called aromatic digestive tonics or aromatic bitters) may be used to relieve symptoms of indigestion, particularly when there is excessive gas. It is believed that carminative agents work, at least in part, by relieving spasms in the intestinal tract.28

    There are numerous carminative herbs, including European angelica root (Angelica archangelica), anise, Basil, cardamom, cinnamon, cloves, coriander, dill, ginger, oregano, rosemary, sage, lavender, and thyme.29 Many of these are common kitchen herbs and thus are readily available for making tea to calm an upset stomach. Rosemary is sometimes used to treat indigestion in the elderly by European herbal practitioners.30 The German Commission E monograph suggests a daily intake of 4–6 grams of sage leaf.31 Pennyroyal is no longer recommended for use in people with indigestion, however, due to potential side effects.

    Demulcents herbs may be used to treat indigestion and heartburn. These herbs seem to work by decreasing inflammation and forming a physical barrier against stomach acid or other abdominal irritants. Examples of demulcent herbs include ginger, licorice, and slippery elm.

    Ginger is a spice well known for its traditional use as a treatment for a variety of gastrointestinal complaints, ranging from flatulence to ulcers. Ginger has anti-inflammatory and anti-nausea properties. Ginger has been shown to enhance normal, spontaneous movements of the intestines that aid digestion.32

    Irritable Bowel Syndrome

    A standardized Chinese herbal combination containing extracts from plants including wormwood, ginger, bupleurum, schisandra, and dan shen reduced IBS symptoms in one study.
    Irritable Bowel Syndrome
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    Whole peppermint leaf is often used either alone or in combination with other herbs to treat abdominal discomfort and mild cramping that accompany IBS. The combination of peppermint, caraway seeds, fennel seeds, and wormwood was reported to be an effective treatment for upper abdominal complaints in a double-blind trial.33

  • Joint Health

    Osteoarthritis

    Ginger has historically been used for arthritis and rheumatism. Studies have shown it to be effective at relieving pain and swelling in people with osteoarthritis.
    Osteoarthritis
    ×
    Ginger has historically been used for arthritis and rheumatism. A preliminary trial reported relief in pain and swelling among people with arthritis who used powdered ginger supplements34 More recently, a double-blind trial found ginger extract (170 mg three times a day for three weeks) to be slightly more effective than placebo at relieving pain in people with osteoarthritis of the hip or knee.35 In another double-blind study, a concentrated extract of ginger, taken in the amount of 255 mg twice daily for six weeks, was significantly more effective than a placebo, as determined by the degree of pain relief and overall improvement.36

    Low Back Pain

    Herbalists often use ginger to decrease inflammation and the pain associated with it, including for those with low back pain.
    Low Back Pain
    ×
     

    Herbalists often use ginger to decrease inflammation and the pain associated with it, including for those with low back pain. They typically suggest 1.5 to 3 ml of ginger tincture three times per day, or 2 to 4 grams of the dried root powder two to three times per day. Some products contain a combination of curcumin and ginger. However, no research has investigated the effects of these herbs on low back pain.

    Rheumatoid Arthritis

    Ginger is an Ayurvedic herb used to treat people with arthritis. Taking fresh or powdered ginger may reduce the symptoms of rheumatoid arthritis.
    Rheumatoid Arthritis
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    Ginger is another Ayurvedic herb used to treat people with arthritis. A small number of case studies suggest that taking 6–50 grams of fresh or powdered ginger per day may reduce the symptoms of RA.37 A combination formula containing ginger, turmeric, boswellia, and ashwagandha has been shown in a double-blind trial to be slightly more effective than placebo for RA;38 the amounts of herbs used in this trial are not provided by the investigators.

  • Menstrual and PMS Support

    Dysmenorrhea

    In a double-blind trial, ginger powder was as effective as anti-inflammatory medication (mefenamic acid and ibuprofen) in relieving symptoms of dysmenorrhea.
    Dysmenorrhea
    ×

    Ginger has been used in some systems of traditional medicine to treat dysmenorrhea. In a double-blind trial, ginger powder was as effective as anti-inflammatory medication (mefenamic acid and ibuprofen) in relieving symptoms of dysmenorrhea. Ginger was used in the amount of 250 mg four times per day, beginning at the start of menstruation and continuing for three days.39 In another double-blind trial, 500 mg of ginger taken 3 times per day, beginning 2 days before menstruation and continuing for the first 3 days of the menstrual period, significantly decreased the duration and severity of menstrual pain, compared with a placebo. The treatment was somewhat less effective if it was started at the beginning of menstruation, rather than 2 days before.40

    Menorrhagia

    In one trial, supplementation with ginger powder decreased the amount of menstrual bleeding in teenage girls who had been experiencing heavy menstrual bleeding.
    Menorrhagia
    ×
    In a 3-month double-blind trial, supplementation with ginger powder significantly decreased the amount of menstrual bleeding by 47% in teenage girls who had been experiencing heavy menstrual bleeding. The amount of ginger used was 250 mg 3 times per day, starting each cycle on the day before menstruation and continuing for a total of 4 days.41
  • Women's Health

    Dysmenorrhea

    In a double-blind trial, ginger powder was as effective as anti-inflammatory medication (mefenamic acid and ibuprofen) in relieving symptoms of dysmenorrhea.
    Dysmenorrhea
    ×

    Ginger has been used in some systems of traditional medicine to treat dysmenorrhea. In a double-blind trial, ginger powder was as effective as anti-inflammatory medication (mefenamic acid and ibuprofen) in relieving symptoms of dysmenorrhea. Ginger was used in the amount of 250 mg four times per day, beginning at the start of menstruation and continuing for three days.42 In another double-blind trial, 500 mg of ginger taken 3 times per day, beginning 2 days before menstruation and continuing for the first 3 days of the menstrual period, significantly decreased the duration and severity of menstrual pain, compared with a placebo. The treatment was somewhat less effective if it was started at the beginning of menstruation, rather than 2 days before.43

    Menorrhagia

    In one trial, supplementation with ginger powder decreased the amount of menstrual bleeding in teenage girls who had been experiencing heavy menstrual bleeding.
    Menorrhagia
    ×
    In a 3-month double-blind trial, supplementation with ginger powder significantly decreased the amount of menstrual bleeding by 47% in teenage girls who had been experiencing heavy menstrual bleeding. The amount of ginger used was 250 mg 3 times per day, starting each cycle on the day before menstruation and continuing for a total of 4 days.44
  • Pain Management

    Migraine Headache

    Anecdotal evidence suggests ginger may be used for migraines and the accompanying nausea.
    Migraine Headache
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    Anecdotal evidence suggests ginger may be used for migraines and the accompanying nausea. In a double-blind study, a sublingual preparation that contained both feverfew and ginger LipiGesic M (PuraMed BioScience, Inc., Schofield, WI) appeared to be beneficial for acute migraines.45 In another double-blind study, a single administration of 250 mg of ginger powder was as effective as the migraine drug, sumatriptan, in the treatment of acute migraines.46

    Low Back Pain

    Herbalists often use ginger to decrease inflammation and the pain associated with it, including for those with low back pain.
    Low Back Pain
    ×
     

    Herbalists often use ginger to decrease inflammation and the pain associated with it, including for those with low back pain. They typically suggest 1.5 to 3 ml of ginger tincture three times per day, or 2 to 4 grams of the dried root powder two to three times per day. Some products contain a combination of curcumin and ginger. However, no research has investigated the effects of these herbs on low back pain.

  • Immune System Support

    Pre- and Post-Surgery Health

    Ginger has antinausea properties and may prevent postoperative nausea and vomiting.
    Pre- and Post-Surgery Health
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    A recent study found that 24% of surgery patients had taken herbal supplements before their surgeries, and 50 different herbs had been used among these patients.47 Little research exists, however, on the safety or efficacy of herbs before surgery. Some researchers and healthcare providers are concerned about possible harmful interactions between herbs and medications used around or during surgery, or the possibility that some herbs may increase bleeding during and after surgery.48,49 The use of herbs around the time of surgery should be discussed with a knowledgeable healthcare practitioner.

    Nausea and vomiting can be experienced post-operatively as a result of anesthesia. Ginger (Zingiber officinale) has antinausea properties and has been examined for its ability to prevent post-operative nausea and vomiting in several controlled trials. In two of these controlled trials, ginger was found more effective than placebo and equal to an antinausea medication;50,51 however, in two other controlled trials ginger was not found to have any benefit.52,53 A review considering the results of these trials concluded that 1 gram of ginger taken before surgery prevents nausea and vomiting slightly better than placebo, but this difference is not significant.54 However, a more recent review concluded that ginger is an effective means for reducing postoperative nausea and vomiting.55

    HIV and AIDS Support

    The herbal formula sho-saiko-to has been shown to have beneficial immune effects on white blood cells in people infected with HIV.
    HIV and AIDS Support
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    The Chinese herb bupleurum, as part of the herbal formula sho-saiko-to, has been shown to have beneficial immune effects on white blood cells taken from people infected with HIV.56 Sho-saiko-to has also been shown to improve the efficacy of the anti-HIV drug lamivudine in the test tube.57 One preliminary study found that 7 of 13 people with HIV given sho-saiko-to had improvements in immune function.58 Double-blind trials are needed to determine whether bupleurum or sho-saiko-to might benefit people with HIV infection or AIDS. Other herbs in sho-saiko-to have also been shown to have anti-HIV activity in the test tube, most notably Asian scullcap.59 Therefore studies on sho-saiko-to cannot be taken to mean that bupleurum is the only active herb involved. The other ingredients are peony root, pinellia root, cassia bark, ginger root, jujube fruit, Asian ginseng root, Asian scullcap root, and licorice root.

  • Ear Health Support

    Vertigo

    Ginger has been shown to be effective at reducing symptoms.
    Vertigo
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    One gram of powdered ginger (Zingiber officinale) root in a single application has been reported to significantly reduce symptoms of artificially induced vertigo in one double-blind trial.60 In a double-blind trial, 1 gram of powdered ginger root was found to have very little effect in reducing vertigo related to seasickness.61

  • Heart and Circulatory Health

    Atherosclerosis

    Supplementing with ginger may reduce platelet stickiness.
    Atherosclerosis
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    The research on ginger’s ability to reduce platelet stickiness indicates that 10 grams (approximately 1 heaping teaspoon) per day is the minimum necessary amount to be effective.62 Lower amounts of dry ginger,63 as well as various levels of fresh ginger,64 have not been shown to affect platelets.

  • Allergy and Lung Support

    Hay Fever

    The Japanese herbal formula known as sho-seiryu-to has been shown to reduce symptoms, such as sneezing, for people with hay fever.
    Hay Fever
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    The Japanese herbal formula known as sho-seiryu-to has been shown to reduce symptom, such as sneezing, for people with hay fever.65 Sho-seiryu-to contains licorice, cassia bark, schisandra, ma huang, ginger, peony root, pinellia, and asiasarum root.

What Are Star Ratings?
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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Traditional Use (May Not Be Supported by Scientific Studies)

Traditional Chinese Medicine has recommended ginger for over 2,500 years. It is used for abdominal bloating, coughing, vomiting, diarrhea, and rheumatism. Ginger is commonly used in the Ayurvedic and Tibb systems of medicine for the treatment of inflammatory joint diseases, such as arthritis and rheumatism.

References

1. Tyler VE. Herbs of Choice: The Therapeutic Use of Phytomedicinals. Binghamton, NY: Pharmaceutical Products Press, 1994, 39-42.

2. Holtmann S, Clarke AH, Scherer H, Hohn M. The anti-motion sickness mechanism of ginger. A comparative study with placebo and dimenhydrinate. Acta Otolaryngol (Stockh) 1989;108:168-74.

3. Grontved A, Brask T, Kambskard J, Hentzer E. Ginger root against sea sickness. A controlled trial in the open sea. Acta Otolarygol 1988;105:45-9.

4. Ribenfeld D, Borzone L. Randomized double-blind study comparing ginger (Zintona®) with dimenhydrinate in motion sickness. Healthnotes Rev Complementary Integrative Med 1999;6:98-101.

5. Careddu P. Motion sickness in children: results of a double-blind study with ginger (Zintona®) and dimenhydrinate. Healthnotes Rev Complementary Integrative Med 1999;6:102-7.

6. Bone ME, Wilkinson DJ, Young JR, et al. Ginger root—a new antiemetic. The effect of ginger root on the postoperative nausea and vomiting after major gynaecological surgery. Anaesthesia 1990;45:669-71.

7. Phillips S, Ruggier R, Hutchinson SE. Zingiber officinale (ginger)—an antiemetic for day case surgery. Anaesthesia 1993;48:715-7.

8. Arfeen Z, Owen H, Plummer JL, et al. A double-blind randomized controlled trial of ginger for the prevention of postoperative nausea and vomiting. Anaesth Intensive Care 1995;23:449-52.

9. Meyer K, Schwartz J, Crater D, Keyes B. Zingiber officinale (ginger) used to prevent 8-Mop associated nausea. Dermatol Nurs 1995;7:242-4.

10. Langner E, Greifenberg S, Gruenwald J. Ginger: History and use. Adv Ther 1998;15:25-44 [review].

11. Bradley PR (ed). British Herbal Compendium, vol 1. Bournemouth, Dorset, UK: British Herbal Medicine Association, 1992, 112-4.

12. Yamahara J, Huang QR, Li YH, et al. Gastrointestinal motility enhancing effect of ginger and its active constituents. Chem Pharm Bull 1990;38:430-1.

13. al-Yahya MA, Rafatullah S, Mossa JS, et al. Gastroprotective activity of ginger in albino rats. Am J Chinese Med 1989;17:51-6.

14. Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc) and fenugreek (Trigonella foenumgraceum L) on blood lipids, blood sugar, and platelet aggregation in patients with coronary artery disease. Prostagland Leukotrienes Essential Fatty Acids 1997;56:379-84.

15. Verma SK, Singh J, Khamesra R, Bordia A. Effect of ginger on platelet aggregation in man. Indian J Med Res 1994;98:240-2.

16. Lumb AB. Effect of dried ginger on human platelet function. Thromb Haemost 1994;7:110-1.

17. Janssen PL, Meyboom S, van Staveren WA, et al. Consumption of ginger (Zingiber officinale Roscoe) does not affect ex vivo platelet thromboxane production in humans. Eur J Clin Nutr 1996;50:772-4.

18. Fischer-Rasmussen W, Kjaer SK, Dahl C, Asping U. Ginger treatment of hyperemesis gravidarum. Eur J Obstet Gynecol Reprod Biol 1991;38:19-24.

19. Borrelli F, Capasso R, Aviello G, et al. Effectiveness and safety of ginger in the treatment of pregnancy-induced nausea and vomiting. Obstet Gynecol 2005;105:849-56.

20. Fulder S, Tenne M. Ginger as an anti-nausea remedy in pregnancy and the issue of safety. HerbalGram 1996;38:47-50.

21. Mowrey DB, Clayson DE. Motion sickness, ginger, and psychophysics. Lancet 1982;1:655-7.

22. Grontved A, Brask T, Kambskard J, Hentzer E. Ginger root against sea sickness. A controlled trial in the open sea. Acta Otolarygol 1988;105:45-9.

23. Ribenfeld D, Borzone L. Randomized double-blind study comparing ginger (Zintona®) with dimenhydrinate in motion sickness. Healthnotes Rev Complementary Integrative Med 1999;6:98-101.

24. Careddu P. Motion sickness in children: results of a double-blind study with ginger (Zintona®) and dimenhydrinate. Healthnotes Rev Complementary Integrative Med 1999;6:102-7.

25. Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991;42:111-20.

26. Holtmann S, Clarke AH, Scherer H, Hohn M. The anti-motion sickness mechanism of ginger. A comparative study with placebo and dimenhydrinate. Acta Otolaryngol (Stockh) 1989;108:168-74.

27. Grontved A, Hentzer E. Vertigo-reducing effect of ginger root. A controlled clinical study. ORL J Otorhinolaryngol Relat Spec 1986;48:282-6.

28. Forster HB, Niklas H, Lutz S. Antispasmodic effects of some medicinal plants. Planta Med 1980;40:303-19.

29. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 425-6.

30. Weiss RF. Herbal Medicine. Beaconsfield, UK: Beaconsfield Publishers Ltd, 1988, 185-6.

31. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 198.

32. Micklefield GH, Redeker Y, Meister V, et al. Effects of ginger on gastroduodenal motility. Int J Clin Pharmacol Ther 1999;37:341-6.

33. Westphal J, Hörning M, Leonhardt K. Phytotherapy in functional upper abdominal complaints. Results of a clinical study with a preparation of several plants. Phytomedicine 1996;2:285-91.

34. Srivastava KC, Mustafa T. Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypoth 1992;39:342-8.

35. Bliddal H, Rosetzsky A, Schlichting P, et al. A randomized, placebo-controlled crossover study of ginger extracts and ibuprofen in osteoarthritis. Osteoarthritis Cartilage 2000;8:9-12.

36. Altman RD, Marcussen KC. Effects of a ginger extract on knee pain in patients with osteoarthritis. Arthritis Rheum 2001;44:2531-8.

37. Srivastava KC, Mustafa T. Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders. Med Hypoth 1992;39:342-8.

38. Chopra A, Lavin P, Patwardhan B, Chitre D. Randomized double blind trial of an Ayurvedic plant derived formulation for treatment of rheumatoid arthritis. J Rheumatol 2000;27:1365-72.

39. Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med 2009;15:129-32.

40. Rahnama P, Montazeri A, Huseini HF, et al. Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial. BMC Complement Altern Med 2012;12:92.

41. Kashefi F, Khajehei M, Alavinia M, et al. Effect of ginger (Zingiber officinale) on heavy menstrual bleeding: a placebo-controlled, randomized clinical trial. Phytother Res 2015;29:114–­9.

42. Ozgoli G, Goli M, Moattar F. Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med 2009;15:129-32.

43. Rahnama P, Montazeri A, Huseini HF, et al. Effect of Zingiber officinale R. rhizomes (ginger) on pain relief in primary dysmenorrhea: a placebo randomized trial. BMC Complement Altern Med 2012;12:92.

44. Kashefi F, Khajehei M, Alavinia M, et al. Effect of ginger (Zingiber officinale) on heavy menstrual bleeding: a placebo-controlled, randomized clinical trial. Phytother Res 2015;29:114–­9.

45. Cady RK, Goldstein J, Nett R, et al. A double-blind placebo-controlled pilot study of sublingual feverfew and ginger (LipiGesic M) in the treatment of migraine. Headache 2011;51:1078-86

46. Maghbooli M, Golipour F, Moghimi et al. Comparison between the efficacy of ginger and sumatriptan in the ablative treatment of the common migraine. Phytother Res. 2014;28:412–5.

47. Norred CL, Zamudio S, Palmer SK. Use of complementary and alternative medicines by surgical patients. AANA J 2000;68:13-8.

48. Murphy JM. Preoperative considerations with herbal medicines. AORN J 1999;69:173-5, 177-8, 180-3.

49. Robb-Nicholson C. By the way, doctor. My surgeon advised me to stop taking gingko biloba before my hip surgery. Can you explain why? Are there any other herbs I should avoid? Harv Womens Health Watch 2000;7:8.

50. Phillips S, Ruggier R, Hutchinson SE. Zingiber officinale (ginger)—an antiemetic for day case surgery. Anaesthesia 1993;48:715-7.

51. Bone ME, Wilkinson DJ, Young JR, et al. Ginger root—a new antiemetic. The effect of ginger root on the postoperative nausea and vomiting after major gynaecological surgery. Anaesthesia 1990;45:669-71.

52. Visalyaputra S, Petchpaisit N, Somcharoen K, Choavaratana R. The efficacy of ginger root in the prevention of postoperative nausea and vomiting after outpatient gynaecological laparoscopy. Anaesthesia 1998;53:506-10.

53. Arfeen Z, Owen H, Plummer JL, et al. A double-blind randomized controlled trial of ginger for the prevention of postoperative nausea and vomiting. Anaesth Intensive Care 1995;23:449-52.

54. Ernst E, Pittler MH. Efficacy of ginger for nausea and vomiting: a systematic review of randomized clinical trials. Br J Anaesth 2000;84:367-71 [review].

55. Chaiyakunapruk N, Kitikannakorn N, Nathisuwan S, et al. The efficacy of ginger for the prevention of postoperative nausea and vomiting: a meta-analysis. Am J Obstet Gynecol2006;194:95-9.

56. Inada Y, Watanabe K, Kamiyama M, et al. In vitro immunomodulatory effects of traditional Kampo medicine (sho-saiko-to: SST) on peripheral mononuclear cells in patients with AIDS. Biomed Pharmacother 1990;44:17-9.

57. Piras G, Makino M, Baba M. Sho-saiko-to, a traditional kampo medicine, enhances the anti-HIV-1 activity of lamivudine (3TC) in vitro. Microbiol Immunol 1997;41:835-9.

58. Fujimaki M, Hada M, Ikematsu S, et al. Clinical efficacy of two kinds of kampo medicine on HIV infected patients. Int Conf AIDS 1989;5:400 [abstract no. W.B.P.292].

59. Li BQ, Fu T, Yan YD, et al. Inhibition of HIV infection by baicalin—a flavonoid compound purified from Chinese herbal medicine. Cell Mol Biol Res 1993;39:119-24.

60. Grontved A, Hentzer E. Vertigo-reducing effect of ginger root. A controlled clinical study. ORL J Otorhinolaryngol Relat Spec 1986;48:282-6.

61. Grontved A, Brask T, Kambskard J, Hentzer E. Ginger root against sea sickness. A controlled trial in the open sea. Acta Otolarygol 1988;105:45-9.

62. Bordia A, Verma SK, Srivastava KC. Effect of ginger (Zingiber officinale Rosc) and fenugreek (Trigonella foenumgraceum L) on blood lipids, blood sugar, and platelet aggregation in patients with coronary artery disease. Prostagland Leukotrienes Essential Fatty Acids 1997;56:379-84.

63. Lumb AB. Effect of dried ginger on human platelet function. Thromb Haemost 1994;7:110-1.

64. Janssen PL, Meyboom S, van Staveren WA, et al. Consumption of ginger (Zingiber officinale Roscoe) does not affect ex vivo platelet thromboxane production in humans. Eur J Clin Nutr 1996;50:772-4.

65. Baba S, Takasaka T. Double-blind clinical trial of sho-seiryu-to (TJ-19) for perennial nasal allergy. Clin Otolaryngol 1995;88:389-405.

66. Brown DJ. Herbal Prescriptions for Better Health. Rocklin, CA: Prima Publishing, 1996, 111-8.

67. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 135-6.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.