Nutritional Supplement

Cat′s Claw

Side Effects

Although no serious adverse effects have been reported for cat’s claw, there is little known about its safety because most reports have been based on anecdotal evidence. There is one case report in which Parkinson's disease became worse after a man started using cat's claw and improved after cat's claw was discontinued.13 Cat’s claw should be used with caution in people with autoimmune illness, multiple sclerosis, and tuberculosis. Until proven safe, cat’s claw should not be taken by pregnant or breast-feeding women.

References

1. Keplinger H. Oxindole alkaloids having properties stimulating the immunologic system and preparation containing same. US Patent no. 5,302,611, April 12, 1994.

2. Aquino R, De Feo V, De Simone F, et al. Plant metabolites, new compounds and anti-inflammatory activity of Uncaria tomentosa. J Nat Prod 1991;54:453-9.

3. Rizzi R, Re F, Bianchi A, et al. Mutagenic and antimutagenic activities of Uncaria tomentosa and its extracts. J Ethnopharmacol 1993;38:63-77.

4. Piscoya J, Rodriguez Z, Bustamante SA, et al. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. Inflamm Res 2001;50:442-8.

5. Mur E, Hartig F, Eibl G, Schirmer M. Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of Uncaria tomentosa for the treatment of rheumatoid arthritis. J Rheumatol 2002;29:678-81.

6. Piscoya J, Rodriguez Z, Bustamante SA, et al. Efficacy and safety of freeze-dried cat's claw in osteoarthritis of the knee: mechanisms of action of the species Uncaria guianensis. Inflamm Res 2001;50:442-8.

7. Mur E, Hartig F, Eibl G, Schirmer M. Randomized double blind trial of an extract from the pentacyclic alkaloid-chemotype of Uncaria tomentosa for the treatment of rheumatoid arthritis. J Rheumatol 2002;29:678-81.

8. Keplinger H. Oxindole alkaloids having properties stimulating the immunologic system and preparation containing same. US Patent no. 5,302,611, April 12, 1994.

9. Keplinger UM. Influence of Krallendorn extract on retroviral infection. Zürcher AIDS Kongress Zurich, Switzerland, Oct 16-7, 1992 [abstract in German].

10. Keplinger UM. Therapy of HIV-infected individuals in the pathological categories CDC A1 and CDC B2 with a preparation containing IMM-207. IV. Österreichischer AIDS-Kongress, Vienna, Austria, Sept 17-8, 1993, 45 [abstract].

11. Foster S. Herbs for Your Health. Loveland, CO: Interweave Press, 1996, 18-9.

12. Foster S. Herbs for Your Health. Loveland, CO: Interweave Press, 1996, 18-9.

13. Cosentino C, Torres L. Reversible worsening of Parkinson's disease motor symptoms after oral intake of Uncaria tomentosa (cat's claw). Clin Neuropharmacol 2008;31:293-4.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.