Nutritional Supplement

Boron

  • Joint Health

    Osteoarthritis

    Boron affects calcium metabolism, and people with OA have been reported to have low bone stores of boron. Supplementing with boron may replenish stores and improve symptoms.
    Osteoarthritis
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    Boron affects calcium metabolism, and a link between boron deficiency and arthritis has been suggested.1 Although people with osteoarthritis have been reported to have lower stores of boron in their bones than people without the disease, other minerals also are deficient in the bones of people with osteoarthritis.2 One double-blind trial found that 6 mg of boron per day, taken for two months, relieved symptoms of osteoarthritis in five of ten people, compared with improvement in only one of the ten people assigned to placebo.3This promising finding needs confirmation from larger trials.

    Rheumatoid Arthritis

    Boron supplementation may be beneficial, particularly in treating people with juvenile rheumatoid arthritis.
    Rheumatoid Arthritis
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    Boron supplementation at 3–9 mg per day may be beneficial, particularly in treating people with juvenile RA, according to very preliminary research.4 The benefit of using boron to treat people with RA remains unproven.

  • Bone Support

    Osteoporosis

    Supplementing with boron has been reported to reduce urinary loss of calcium and magnesium. However, those already supplementing with magnesium appear to achieve no additional calcium-sparing benefit when boron is added. Therefore, people with osteoporosis should supplement with magnesium or boron, not both.
    Osteoporosis
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    Boron supplementation has been reported to reduce urinary loss of calcium and magnesium in some,5 but not all,6 preliminary research. However, those who are already supplementing with magnesium appear to achieve no additional calcium-sparing benefit when boron is added.7 Finally, in the original report claiming that boron reduced loss of calcium,5 the effect was achieved by significantly increasing estrogen and testosterone levels, hormones that have been linked to cancer risks. Therefore, it makes sense for people with osteoporosis to supplement with magnesium instead of, rather than in addition to, boron.

    One trial studying postmenopausal women combined hormone replacement therapy with magnesium (600 mg per day), calcium (500 mg per day), vitamin C, B vitamins, vitamin D, zinc, copper, manganese, boron, and other nutrients for an eight- to nine-month period.9 In addition, participants were told to avoid processed foods, limit protein intake, emphasize vegetable over animal protein, and limit consumption of salt, sugar, alcohol, coffee, tea, chocolate, and tobacco. Bone density increased a remarkable 11%, compared to only 0.7% in women receiving hormone replacement alone.

What Are Star Ratings?
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Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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References

1. Newnham RE. The role of boron in human nutrition. J Applied Nutr 1994;46:81-5.

2. Helliwell TR, Kelly SA, Walsh HP, et al. Elemental analysis of femoral bone from patients with fractured neck of femur or osteoarthrosis. Bone 1996;18:151-7.

3. Travers RL, Rennie GC, Newnham RE. Boron and arthritis: the results of a double-blind pilot study. J Nutr Med 1990;1:127-32.

4. Newnham RE. Arthritis or skeletal fluorosis and boron. Int Clin Nutr Rev 1991;11:68-70 [letter].

5. Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J 1987;1:394-7.

6. Meacham SL, Taper LJ, Volpe SL. Effect of boron supplementation on blood and urinary calcium, magnesium, and phosphorus, and urinary boron in athletic and sedentary women. Am J Clin Nutr 1995;61:341-5.

7. Hunt CD, Herbel JL, Nielsen FH. Metabolic responses of postmenopausal women to supplemental dietary boron and aluminum during usual and low magnesium intake: boron, calcium, and magnesium absorption and retention and blood mineral concentrations. Am J Clin Nutr 1997;65:803-13.

8. Abraham GE, Grewal H. A total dietary program emphasizing magnesium instead of calcium. J Reprod Med 1990;35:503-7.

9. Nielsen FH. Facts and fallacies about boron. Nutr Today 1992(May/Jun):6-12.

10. Kelly GS. Boron: a review of its nutritional interactions and therapeutic uses. Altern Med Rev 1997;2:48-56 [review].

11. Nielsen FH. Ultratrace minerals: Boron. In: Shils ME, Young VR (eds). Modern Nutrition in Health and Disease. Philadelphia: Lea & Febiger 1988, 281-3 [review].

12. Nielsen FH, Penland JG. Boron supplementation of peri-menopausal women affects boron metabolism and indices associated with macromineral metabolism, hormonal status and immune function. J Trace Elem Exp Med 1999;12:251-61.

13. Nielsen FH, Hunt CD, Mullen LM, Hunt JR. Effect of dietary boron on mineral, estrogen, and testosterone metabolism in postmenopausal women. FASEB J 1987;1:394-7.

14. Nielsen FH, Penland JG. Boron supplementation of per-menopausal women affects boron metabolism and indices associated with macromineral metabolism, hormonal status and immune function. J Trace Elem Exp Med 1999;12:251-61.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.