Diet & Fitness

Beta-sitosterol and sitostanol are examples of phytosterols, plant compounds related to cholesterol. Phytosterols reduce dietary cholesterol absorption and alter cholesterol metabolism, and numerous clinical trials and meta-analyses have found dietary and supplemental phytosterols, especially sitosterols and sitostanols, lower cholesterol levels.⁴ In particular, clinical trials using margarine and other foods enriched with highly-absorbable sitostanol esters have noted substantial improvements in lipid profiles with an intake of 2–3 grams of sitostanol esters daily.⁵ Findings from research reviews indicate long-term use of 2 grams of sitostanols and sitosterols daily can reduce LDL-cholesterol levels by as much as 10–20%.^6,7 Supplementation with beta-sitosterol or sitostanol has also been shown to enhance the cholesterol-lowering effect of statin drugs.⁸ In addition to improving lipid levels, beta-sitosterol has demonstrated anti-inflammatory, antioxidant, anti-diabetic, immune-modulating, liver-protective, and anti-anxiety properties that may add to its health-promoting effects.⁹

 

Beta-sitosterol, a compound found in many edible plants, has also been found to be helpful for men with BPH. In one double-blind trial, 200 men with BPH received 20 mg of beta-sitosterol three times a day or a placebo for six months. Men receiving beta-sitosterol had a significant improvement in urinary flow and an improvement in symptoms, whereas no change was reported in men receiving the placebo.¹⁰ Another double-blind study reported similarly positive results using 130 mg per day of beta-sitosterol.¹¹

Beta-sitosterol, (BSS) a natural sterol found in many plants, has been shown in a double-blind trial to improve immune function in marathon runners when combined with a related substance called B-sitosterol glucoside (BSSG).¹² This implies that beta-sitosterol might reduce infections in athletes who engage in intensive exercise, though studies are still needed to prove this. The usual amount of this combination used in research is 20 mg of BSS and 200 mcg of BSSG three times per day.

Beta-sitosterol, (BSS) a natural sterol found in many plants, has been shown in a double-blind trial to improve immune function in marathon runners when combined with a related substance called B-sitosterol glucoside (BSSG).¹³ This implies that beta-sitosterol might reduce infections in athletes who engage in intensive exercise, though studies are still needed to prove this. The usual amount of this combination used in research is 20 mg of BSS and 200 mcg of BSSG three times per day.