Health Condition

Iron-Deficiency Anemia

  • Iron

    Supplementing with iron is essential to treating iron deficiency.

    Dose:

    Consult a qualified healthcare practitioner
    Iron
    ×

    Caution: People should not supplement with iron unless diagnosed with iron deficiency, because taking iron when it isn’t needed has no benefit and may be harmful.

    Before iron deficiency can be treated, it must be diagnosed and the cause must be found by a doctor. In addition to addressing the cause (e.g., avoiding aspirin, treating a bleeding ulcer, etc.), supplementation with iron is the primary way to resolve iron-deficiency anemia.

    If a doctor diagnoses iron deficiency, iron supplementation is essential. Though some doctors use higher amounts, a common daily dose for adults is 100 mg per day. Even though symptoms of deficiency should disappear much sooner, iron deficient people usually need to keep supplementing with iron for six months to one year until the ferritin test is completely normal. Even after taking enough iron to overcome the deficiency, some people with recurrent iron deficiency—particularly some premenopausal women—need to continue to supplement with smaller levels of iron, such as the 18 mg present in most multivitamin-mineral supplements. This need for continual iron supplementation even after deficiency has been overcome should be determined by a doctor.

  • Liver Extracts

    Bovine liver extracts provide the most absorbable form of iron—heme iron—as well as other nutrients critical in building blood, including vitamin B12 and folic acid.

    Dose:

    If deficient: several grams per day for up to one year under medical supervision
    Liver Extracts
    ×
     

    Liver extracts from beef are a rich natural source of many vitamins and minerals, including iron. Bovine liver extracts provide the most absorbable form of iron—heme iron—as well as other nutrients critical in building blood, including vitamin B12 and folic acid. Liver extracts can contain as much as 3–4 mg of heme iron per gram.

  • Taurine

    Taurine has been shown to improve the response to iron therapy in young women with iron-deficiency anemia.

    Dose:

    1,000 mg daily
    Taurine
    ×
     

    Taurine has been shown, in a double-blind study, to improve the response to iron therapy in young women with iron-deficiency anemia.2 The amount of taurine used was 1,000 mg per day for 20 weeks, given in addition to iron therapy, but at a different time of the day. The mechanism by which taurine improves iron utilization is not known.

  • Vitamin A and Iron

    Taking vitamin A and iron together has been reported to help overcome iron deficiency more effectively than iron supplements alone.

    Dose:

    Consult a qualified healthcare practitioner
    Vitamin A and Iron
    ×
     

    Taking vitamin A and iron together has been reported to help overcome iron deficiency more effectively than iron supplements alone.3 Although the optimal amount of vitamin A needed to help people with iron deficiency has yet to be established, some doctors recommend 10,000 IU per day.

  • Vitamin C and Iron

    Taking vitamin C with iron supplements has been shown to improve iron absorption. 

    Dose:

    Take 100 to 500 mg of vitamin C with iron supplements with a doctor's supervision
    Vitamin C and Iron
    ×

    Caution: People who are not diagnosed with iron deficiency should not supplement with iron. Taking iron when it isn’t needed has no benefit and may do some harm.

    Vitamin C increases the absorption of non-heme iron.4 Some doctors advise iron-deficient people to take vitamin C (typically 100–500 mg) at the same time as their iron supplement.5
  • Betaine Hydrochloride and Iron

    Hydrochloric acid produced by the stomach improves the absorption of non-heme iron. Some practitioners recommend betaine hydrochloride to enhance iron absorption.

    Dose:

    Refer to label instructions
    Betaine Hydrochloride and Iron
    ×
     

    A high degree of association between iron-deficiency anemia and vitamin D deficiency in Asian children has been previously reported.6 In three different ethnic groups living in England, iron-deficiency anemia was found to be a significant risk factor for low vitamin D levels in children.7 These findings suggest that children with iron-deficiency anemia should be screened for vitamin D deficiency and be given vitamin D supplements if necessary.

What Are Star Ratings
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

References

1. Looker AC, Dallman PR, Carroll MD, et al. Prevalence of iron deficiency in the United States. JAMA 1997;277:973-6.

2. Sirdah MM, El-Agouza IMA, Abu Shahla ANK. Possible ameliorative effect of taurine in the treatment of iron-deficiency anaemia in female university students of Gaza, Palestine. Eur J Haematol 2002;69:236-2.

3. Mejia LA, Chew F. Hematological effect of supplementing anemic children with vitamin A alone and in combination with iron. Am J Clin Nutr 1988;48:595-600.

4. Ajayi OA, Nnaji UR. Effect of ascorbic acid supplementation on haematological response and ascorbic acid status of young female adults. Ann Nutr Metab 1990;34:32-6.

5. Hunt JR, Gallagher SK, Johnson LK. Effect of ascorbic acid on apparent iron absorption by women with low iron stores. Am J Clin Nutr 1994;59:1381-5.

6. Grindulis H, Scott PH, Belton NR, Wharton BA. Combined deficiency of iron and vitamin D in Asian toddlers. Arch Dis Child 1986;61:843-8.

7. Lawson M, Thomas M. Vitamin D concentrations in Asian children aged 2 years living in England: population survey. BMJ 1999;318:28.

8. Cook JD, Noble NL, Morck TA, et al. Effect of fiber on nonheme iron absorption. Gastroenterology 1983;85:1354-8.

9. Sullivan JL. Stored iron and ischemic heart disease. Circulation 1992;86:1036 [editorial].

10. Morck TA, Lynch SR, Cook JD. Inhibition of food iron absorption by coffee. Am J Clin Nutr 1983;37:416–20.

11. Mehta SW, Pritchard ME, Stegman C. Contribution of coffee and tea to anemia among NHANES II participants. Nutr Res 1992;12:209-22.

12. Kaltwasser JP, Werner E, Schalk K, et al. Clinical trial on the effect of regular tea drinking on iron accumulation in genetic haemochromatosis. Gut 1998;43:699-704.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. Self-treatment is not recommended for life-threatening conditions that require medical treatment under a doctor's care. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.