Nutritional Supplement

Black Cohosh

  • Women's Health

    Menopause

    Studies have shown black cohosh to be a safe and effective treatment for women with hot flashes associated with menopause.
    Menopause
    ×
     

    Some, but not all, double-blind trials support the usefulness of black cohosh for women with hot flashes associated with menopause.12 In a three-month study of postmenopausal women, 40 mg per day of an extract of black cohosh was as effective as estrogen therapy in the treatment of hot flashes.13 A review of eight trials concluded black cohosh to be both safe and effective.14 However, one double-blind trial found that black cohosh is ineffective as a treatment for menopausal symptoms.15 Many doctors recommend 20 mg of a highly concentrated extract taken twice per day; 2 to 4 ml of tincture three times per day may also be used.

    In a double-blind study of postmenopausal women who were experiencing psychological symptoms, a combination of black cohosh and St. John's wort was significantly more effective than a placebo in improving both menopausal symptoms and depression. The product used in this study contained (per tablet) black cohosh standardized to 1 mg of triterpene glycosides and St. John's wort standardized to 0.25 mg of hypericin. The amount taken was two tablets twice a day for eight weeks, followed by one tablet twice a day for eight weeks.16

    Menopause and Depression

    Menopausal and depression symptoms improved in post-menopausal women after they took a combination of black cohosh and St. John's wort.
    Menopause and Depression
    ×
    In a double-blind study of postmenopausal women who were experiencing psychological symptoms, a combination of black cohosh and St. John's wort was significantly more effective than a placebo in improving both menopausal symptoms and depression. The product used in this study contained (per tablet) black cohosh standardized to 1 mg of triterpene glycosides and St. John's wort standardized to 0.25 mg of hypericin. The amount taken was two tablets twice a day for eight weeks, followed by one tablet twice a day for eight weeks.17

    Premenstrual Syndrome

    Black cohosh has been historically used to treat PMS.
    Premenstrual Syndrome
    ×
     

    Black cohosh is approved in Germany for use in women with PMS.18 This approval appears to be based on historical use as there are no modern clinical trials to support the use of black cohosh for PMS.

    Dysmenorrhea

    Black cohosh has a history as a folk medicine for relieving menstrual cramps.
    Dysmenorrhea
    ×
     

    Black cohosh has a history as a folk medicine for relieving menstrual cramps. Black cohosh can be taken in several forms, including crude plant, dried root, or rhizome (300–2,000 mg per day), or as a solid, dry powdered extract (250 mg three times per day). Standardized extracts of the herb are available, though they have primarily been researched for use with menopausal women suffering from hot flashes. The recommended amount is 20–40 mg twice per day.19 The best researched form provides 1 mg of deoxyactein per 20 mg of extract. Tinctures can are also used (2–4 ml three times per day).20 The Commission E Monograph recommends black cohosh be taken for up to six months, and then discontinued.21

  • Menopause Support

    Menopause

    Studies have shown black cohosh to be a safe and effective treatment for women with hot flashes associated with menopause.
    Menopause
    ×
     

    Some, but not all, double-blind trials support the usefulness of black cohosh for women with hot flashes associated with menopause.22 In a three-month study of postmenopausal women, 40 mg per day of an extract of black cohosh was as effective as estrogen therapy in the treatment of hot flashes.23 A review of eight trials concluded black cohosh to be both safe and effective.24 However, one double-blind trial found that black cohosh is ineffective as a treatment for menopausal symptoms.25 Many doctors recommend 20 mg of a highly concentrated extract taken twice per day; 2 to 4 ml of tincture three times per day may also be used.

    In a double-blind study of postmenopausal women who were experiencing psychological symptoms, a combination of black cohosh and St. John's wort was significantly more effective than a placebo in improving both menopausal symptoms and depression. The product used in this study contained (per tablet) black cohosh standardized to 1 mg of triterpene glycosides and St. John's wort standardized to 0.25 mg of hypericin. The amount taken was two tablets twice a day for eight weeks, followed by one tablet twice a day for eight weeks.26

    Menopause and Depression

    Menopausal and depression symptoms improved in post-menopausal women after they took a combination of black cohosh and St. John's wort.
    Menopause and Depression
    ×
    In a double-blind study of postmenopausal women who were experiencing psychological symptoms, a combination of black cohosh and St. John's wort was significantly more effective than a placebo in improving both menopausal symptoms and depression. The product used in this study contained (per tablet) black cohosh standardized to 1 mg of triterpene glycosides and St. John's wort standardized to 0.25 mg of hypericin. The amount taken was two tablets twice a day for eight weeks, followed by one tablet twice a day for eight weeks.27
  • Menstrual and PMS Support

    Premenstrual Syndrome

    Black cohosh has been historically used to treat PMS.
    Premenstrual Syndrome
    ×
     

    Black cohosh is approved in Germany for use in women with PMS.28 This approval appears to be based on historical use as there are no modern clinical trials to support the use of black cohosh for PMS.

    Dysmenorrhea

    Black cohosh has a history as a folk medicine for relieving menstrual cramps.
    Dysmenorrhea
    ×
     

    Black cohosh has a history as a folk medicine for relieving menstrual cramps. Black cohosh can be taken in several forms, including crude plant, dried root, or rhizome (300–2,000 mg per day), or as a solid, dry powdered extract (250 mg three times per day). Standardized extracts of the herb are available, though they have primarily been researched for use with menopausal women suffering from hot flashes. The recommended amount is 20–40 mg twice per day.29 The best researched form provides 1 mg of deoxyactein per 20 mg of extract. Tinctures can are also used (2–4 ml three times per day).30 The Commission E Monograph recommends black cohosh be taken for up to six months, and then discontinued.31

  • Bone Support

    Osteoporosis

    Black cohosh has been shown to improve bone mineral density in animals fed a low-calcium diet.
    Osteoporosis
    ×

    Black cohosh has been shown to improve bone mineral density in animals fed a low calcium diet,32 but it has not been studied for this purpose in humans.

What Are Star Ratings?
×
Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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Traditional Use (May Not Be Supported by Scientific Studies)

Native Americans valued the herb and used it for many conditions, ranging from gynecological problems to rattlesnake bites. Some 19th century American physicians used black cohosh for fever, menstrual cramps, arthritis, and insomnia.33

References

1. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs, and Cosmetics, 2d ed. New York: John Wiley & Sons, 1996, 88-9.

2. Castleman M. The Healing Herbs. Emmaus, PA: Rodale Press, 1991, 75-8.

3. Jarry H, Harnischfeger G, DĂĽker E. Studies on endocrine effects of the contents of Cimicifuga racemosa. 2. In vitro binding of compounds to estrogen receptors. Planta Medica 1985;51:316-9.

4. Jarry H, Harnischfeger G. Studies on endocrine effects of the contents of Cimicifuga racemosa. 1. Influence on the serum concentration of pituitary hormones in ovariectomized rats. Planta Medica 1985;51:46-9.

5. DĂĽker EM, Kopanski L, Jarry H, Wuttke W. Effects of extracts from Cimicifuga racemosa on gonadotropin release in menopausal women and ovariectomized rats. Planta Medica 1991;57:420-4.

6. Einer-Jensen N, Zhao J, Andersen KP, Kristoffersen K. Cimicifuga and Melbrosia lack estrogenic effects in mice and rats. Maturitas 1996;25:149-53.

7. Liske E, Wüstenberg P, Boblitz N. Human pharmacological investigations during treatment of climacteric complaints with Cimicifuga racemosa (Remifemin®): No estrogen-like effects [Poster presentation]. 2nd International Congress on Phytomedicine, London, October 15-16, 1998.

8. Stoll W. Phytopharmaceutical influences atrophic vaginal epithelium. Double-blind study on Cimicifuga versus an estrogen preparation. Therapeutikon 1987;1:23-32.

9. Warnecke G. Using phyto-treatment to influence menopause symptoms. Med Welt 1985;36:871-4.

10. Liske E, WĂĽstenberg P. Therapy of climacteric complaints with Cimicifuga racemosa: a herbal medicine with clinically proven evidence [Abstract #98.0020]. Poster Presentation, 9th Annual Meeting of the North American Menopause Society, Toronto, Canada, September 16-9, 1998.

11. Kadota S, Li JX, Li HY, et al. Effects of cimicifugae rhizome on serum calcium and phosphate levels in low calcium dietary rats and on bone mineral density in ovariectomized rats. Phytomed 1996/97;3(4):379-85.

12. Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecological disorders. Advances Therapy 1998;15:45-53.

13. Nappi RE, Malavasi B, Brundu B, Facchinetti F. Efficacy of Cimicifuga racemosa on climacteric complaints: a randomized study versus low-dose transdermal estradiol. Gynecol Endocrinol 2005;20:30-5.

14. Lieberman S. A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause. J Womens Health 1998;7:525-9.

15. Newton KM, Reed SD, LaCroix AZ, et al. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med 2006;145:869-79.

16. Uebelhack R, Blohmer JU, Graubaum HJ, et al. Black cohosh and St. John's wort for climacteric complaints: a randomized trial. Obstet Gynecol 2006;107:247-55.

17. Uebelhack R, Blohmer JU, Graubaum HJ, et al. Black cohosh and St. John's wort for climacteric complaints: a randomized trial. Obstet Gynecol 2006;107:247-55.

18. Blumenthal M, Busse WR, Goldberg A, et al., eds. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 90.

19. Murray MT. The Healing Power of Herbs. Rocklin, CA: Prima Publishing, 1995, 376.

20. Bradley PR, ed. British Herbal Compendium, vol 1. Bournemouth, Dorset, UK: British Herbal Medicine Association, 1992, 34-6.

21. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 90.

22. Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecological disorders. Advances Therapy 1998;15:45-53.

23. Nappi RE, Malavasi B, Brundu B, Facchinetti F. Efficacy of Cimicifuga racemosa on climacteric complaints: a randomized study versus low-dose transdermal estradiol. Gynecol Endocrinol 2005;20:30-5.

24. Lieberman S. A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause. J Womens Health 1998;7:525-9.

25. Newton KM, Reed SD, LaCroix AZ, et al. Treatment of vasomotor symptoms of menopause with black cohosh, multibotanicals, soy, hormone therapy, or placebo: a randomized trial. Ann Intern Med 2006;145:869-79.

26. Uebelhack R, Blohmer JU, Graubaum HJ, et al. Black cohosh and St. John's wort for climacteric complaints: a randomized trial. Obstet Gynecol 2006;107:247-55.

27. Uebelhack R, Blohmer JU, Graubaum HJ, et al. Black cohosh and St. John's wort for climacteric complaints: a randomized trial. Obstet Gynecol 2006;107:247-55.

28. Blumenthal M, Busse WR, Goldberg A, et al., eds. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Austin: American Botanical Council and Boston: Integrative Medicine Communications, 1998, 90.

29. Murray MT. The Healing Power of Herbs. Rocklin, CA: Prima Publishing, 1995, 376.

30. Bradley PR, ed. British Herbal Compendium, vol 1. Bournemouth, Dorset, UK: British Herbal Medicine Association, 1992, 34-6.

31. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 90.

32. Kadota S, Li JX, Li HY, et al. Effects of cimicifugae rhizome on serum calcium and phosphate levels in low calcium dietary rats and on bone mineral density in ovariectomized rats. Phytomed 1996/97;3(4):379-85.

33. Foster S. Herbs for Your Health. Loveland, CO: Interweave Press, 1996, 12-3.

34. Murray MT. The Healing Power of Herbs. Rocklin, CA: Prima Publishing, 1995, 376.

35. Bradley PR, ed. British Herbal Compendium, vol 1. Bournemouth, Dorset, UK: British Herbal Medicine Association, 1992, 34-6.

36. Blumenthal M, Busse WR, Goldberg A, et al. (eds). The Complete Commission E Monographs: Therapeutic Guide to Herbal Medicines. Boston, MA: Integrative Medicine Communications, 1998, 90.

37. Gruenwald J. Standardized black cohosh (Cimicifuga) extract clinical monograph. Quart Rev Nat Med 1998;Summer:117-25.

38. Cohen SM, O'Connor AM, Hart J, et al. Autoimmune hepatitis associated with the use of black cohosh: a case study. Menopause 2004;11:575-7.

39. Levitsky J, Alli TA, Wisecarver J, Sorrell MF. Fulminant liver failure associated with the use of black cohosh. Dig Dis Sci 2005;50:538-9.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.