Nutritional Supplement

Sea Buckthorn

Also indexed as: Buckthorn (Sea), Hippophae rhamnoides
Botanical names:
Hippophae rhamnoides
Common names:
Sea buckthorn

Parts Used & Where Grown

Sea buckthorn berries are used, either as the whole berry, berry puree or juice, or the oil derived from the fruit or its seeds. The plant is native to Europe and Asia.

How It Works

Sea buckthorn berries contain flavonoids such as isorhamnetin,1 as well as vitamins and other factors that might contribute to its activity.2 The oil in the pulp and seed is high in omega-3 and omega-6 fatty acids.3

References

1. Suomela JP, Ahotupa M, Yang B, et al. Absorption of flavonols derived from sea buckthorn (Hippophaërhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans. J Agric Food Chem 2006;54:7364-9.

2. Suryakumar G, Gupta A. Medicinal and therapeutic potential of Sea buckthorn (Hippophaerhamnoides L.). J Ethnopharmacol 2011;138:268-78.

3. Yang B, Kallio HP. Fatty acid composition of lipids in sea buckthorn (Hippophaërhamnoides L.) berries of different origins. J Agric Food Chem 2001;49:1939–47.

4. Lehtonen HM, Suomela JP, Tahvonen R, et al. Different berries and berry fractions have various but slightly positive effects on the associated variables of metabolic diseases on overweight and obese women. Eur J ClinNutr 2011;65:394-401.

5. Natural Medicines Comprehensive Database citation: Zhang MS, et al. Treatment of ischemic heart diseases with flavonoids of Hippophaerhamnoides. Chinese J Cardiol 1987;15:97-9.Pubmed citation: Zhang MS. A control trial of flavonoids of Hippophaerhamnoides L. in treating ischemic heart disease. ZhonghuaXinXue Guan Bing ZaZhi 1987;15:97-9 [in Chinese].

6. Larmo P, Alin J, Salminen E, et al. Effects of sea buckthorn berries on infections and inflammation: a double-blind, randomized, placebo-controlled trial. Eur J ClinNutr 2008;62:1123-30.

7. Suomela JP, Ahotupa M, Yang B, et al. Absorption of flavonols derived from sea buckthorn (Hippophaërhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans. J Agric Food Chem 2006;54:7364-9.

8. Eccleston C, Baoru Y, Tahvonen R et al. Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humans. J Nutr Biochem 2002;13:346–54.

9. Olas B. Sea buckthorn as a source of important bioactive compounds in cardiovascular diseases. Food Chem Toxicol 201697:199–204.

10. Skalski B, Kontek B, Olas B, et al. Phenolic fraction and nonpolar fraction from sea buckthorn leaves and twigs: chemical profile and biological activity. Future Med Chem 2018;10:2381–94.

11. Zhou F, Zhang J, Zhao A, et al. Effects of sea buckthorn puree on risk factors of cardiovascular disease in hypercholesterolemia population: a double-blind, randomized, placebo-controlled trial. Anim Biotechnol 2020:1–9.

12. Vashishtha V, Barhwal K, Kumar A, et al. Effect of seabuckthorn seed oil in reducing cardiovascular risk factors: A longitudinal controlled trial on hypertensive subjects. Clin Nutr 2017;36:1231–8.

13. Olas B. Sea buckthorn as a source of important bioactive compounds in cardiovascular diseases. Food Chem Toxicol 201697:199–204.

14. Zhou F, Zhang J, Zhao A, et al. Effects of sea buckthorn puree on risk factors of cardiovascular disease in hypercholesterolemia population: a double-blind, randomized, placebo-controlled trial. Anim Biotechnol 2020:1–9.

15. Larmo PS, Yang B, Hurme SA, et al. Effect of a low dose of sea buckthorn berries on circulating concentrations of cholesterol, triacylglycerols, and flavonols in healthy adults. Eur J Nutr 2009;48:277–82.

16. Eccleston C, Baoru Y, Tahvonen R et al. Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humans. J Nutr Biochem 2002;13:346–54.

17. Larmo PS, Kangas AJ, Soininen P, et al. Effects of sea buckthorn and bilberry on serum metabolites differ according to baseline metabolic profiles in overweight women: a randomized crossover trial. Am J Clin Nutr 2013;98:941–51.

18. Vashishtha V, Barhwal K, Kumar A, et al. Effect of seabuckthorn seed oil in reducing cardiovascular risk factors: A longitudinal controlled trial on hypertensive subjects. Clin Nutr 2017;36:1231–8.

19. Lehtonen HM, Suomela JP, Tahvonen R, et al. Different berries and berry fractions have various but slightly positive effects on the associated variables of metabolic diseases on overweight and obese women. Eur J ClinNutr 2011;65:394-401.

20. Natural Medicines Comprehensive Database citation: Zhang MS, et al. Treatment of ischemic heart diseases with flavonoids of Hippophaerhamnoides. Chinese J Cardiol 1987;15:97-9.Pubmed citation: Zhang MS. A control trial of flavonoids of Hippophaerhamnoides L. in treating ischemic heart disease. ZhonghuaXinXue Guan Bing ZaZhi 1987;15:97-9 [in Chinese].

21. Larmo P, Alin J, Salminen E, et al. Effects of sea buckthorn berries on infections and inflammation: a double-blind, randomized, placebo-controlled trial. Eur J ClinNutr 2008;62:1123-30.

22. Suomela JP, Ahotupa M, Yang B, et al. Absorption of flavonols derived from sea buckthorn (Hippophaërhamnoides L.) and their effect on emerging risk factors for cardiovascular disease in humans. J Agric Food Chem 2006;54:7364-9.

23. Eccleston C, Baoru Y, Tahvonen R et al. Effects of an antioxidant-rich juice (sea buckthorn) on risk factors for coronary heart disease in humans. J Nutr Biochem 2002;13:346–54.

24. Suryakumar G, Gupta A. Medicinal and therapeutic potential of Sea buckthorn (Hippophaerhamnoides L.). J Ethnopharmacol 2011;138:268-78.

25. Wang ZY, Luo XL, He CP. Management of burn wounds with Hippophaerhamnoides oil. Nan Fang Yi Ke Da XueXueBao 2006;26:124-5 [in Chinese].

26. Ziboh VA The significance of polyunsaturated fatty acids in cutaneous biology. Lipids 1996;31:S249-253 [review].

27. The British Nutrition Foundation. Function of unsaturated fatty acids. In Unsaturated Fatty Acids: Nutrition and Physiological Significance (The Report of The British Nutrition Foundations Task Force). London, UK:Chapman & Hall, 1992, pp. 48-62 [review].

28. Suryakumar G, Gupta A. Medicinal and therapeutic potential of Sea buckthorn (Hippophaerhamnoides L.). J Ethnopharmacol 2011;138:268-78.

29. Yang B, Kalimo KO, Mattila LM, et al. Effects of dietary supplementation with sea buckthorn (Hippophaërhamnoides) seed and pulp oils on atopic dermatitis. J NutrBiochem 1999;10:622-30.

30. Thumm EJ, Stoss M, Bayerl C, Schurholz TH. Randomized trial to study efficacy of a 20% and 10% Hippophaerhamnoides containing creme used by patients with mild to intermediate atopic dermatitis. AktuelleDermatologie 2000;26:285-290 [in German].

31. Suryakumar G, Gupta A. Medicinal and therapeutic potential of Sea buckthorn (Hippophaerhamnoides L.). J Ethnopharmacol 2011;138:268-78.

32. Wang ZY, Luo XL, He CP. Management of burn wounds with Hippophaerhamnoides oil. Nan Fang Yi Ke Da XueXueBao 2006;26:124-5 [in Chinese].

33. Suryakumar G, Gupta A. Medicinal and therapeutic potential of Sea buckthorn (Hippophaerhamnoides L.). J Ethnopharmacol 2011;138:268-78.

34. Larmo P, Alin J, Salminen E, et al. Effects of sea buckthorn berries on infections and inflammation: a double-blind, randomized, placebo-controlled trial. Eur J ClinNutr 2008;62:1123-30.

35. Sea buckthorn contains flavonoids and other constituents that promote healing, and sea buckthorn oil has been shown to both prevent and heal peptic ulcers in animal studies. Direct application of sea buckthorn oil to ulcers during medical treatment with endoscopy has been reported to improve results, but no studies of treating peptic ulcers with sea buckthorn oil supplements have been done.

36. Nikitin VA, Chistiakov AA, Bugaeva VI. Therapeutic endoscopy in combined therapy of gastroduodenal ulcers. Khirurgiia (Mosk) 1989;4:33-35 [in Russian].

37. Miljanovic B, Trivedi KA, Dana MR, et al.Relation between dietary n-3 and n-6 fatty acids and clinically diagnosed dry eye syndrome in women. Am J ClinNutr 2005; 82:887-893.

38. Barabino S, Rolando M, Camicione P, et al. Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. Cornea 2003;22:97-101.

39. Pinheiro MN Jr, dos Santos PM, dos Santos RC, et al. Oral flaxseed oil (Linumusitatissimum) in the treatment for dry-eye Sjögren's syndrome patients. Arq Bras Oftalmol 2007;70:649-55 [in Portuguese].

40. Larmo PS, Järvinen RL, Setälä NL, et al. Oral sea buckthorn oil attenuates tear film osmolarity and symptoms in individuals with dry eye. J Nutr 2010;140:1462-8.

41. Dragan S, Andrica F, Serban M, Timar R. Polyphenols-rich natural products for treatment of diabetes. Curr Med Chem 2015;22:14–22.

42. Lehtonen H, Jarvinen R, Linderborg K, et al. Postprandial hyperglycemia and insulin response are affected by sea buckthorn (Hippophae rhamnoides ssp. turkestanica) berry and its ethanol-soluble metabolites. Eur J Clin Nutr 2010;64:1465–71.

43. Dunca I, et al. Effect of a dietary supplement containing blueberry and sea buckthorn concentrate on antioxidant capacity in type 1 diabetic children. Acta Physiol Hung 2008;95:383–93.

44. Johansson AK, Korte H, Yang B, et al. Sea buckthorn berry oil inhibits platelet aggregation. J NutrBiochem 2000;11:491-5.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2024.