Drug

Clofibrate

Common brand names:

Atromid-S

Clofibrate is a drug used to lower cholesterol in people with high blood cholesterol. It is rarely used, due to the possibility of liver damage and the availability of safer, more effective drugs.

Summary of Interactions with Vitamins, Herbs, & Foods

  • Supportive Interactions

    2
    • Clofibrate

      Vitamin B12

      Replenish Depleted Nutrients

      Clofibrate has been reported to reduce absorption of vitamin B12.

      Vitamin B12
      Clofibrate
      ×
      1. Robinson C, Weigly E. Basic Nutrition and Diet Therapy. New York: Macmillan, 1984, 46-54.
    • Clofibrate

      Milk Thistle

      Reduce Side Effects

      Although there have been no clinical studies, use of milk thistle (Silibum marianum) with clofibrate may theoretically lower the risk of liver side effects associated with the drug. People may take a standardized milk thistle extract supplying 70–80% silymarin at an amount of 200 mg three times per day.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

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