Drug

Brinzolamide-Brimonidine

Common brand names:

Simbrinza

Summary of Interactions with Vitamins, Herbs, & Foods

  • Negative Interactions

    1
    • Brimonidine

      Yohimbe

      Reduces Effectiveness

      The active ingredients in yohimbine can block the actions of brimonidine in certain human tissues, thus reducing the drug’s beneficial effects. Adequate human studies involving the eye are lacking, and until more information is available, yohimbine should be avoided in people using brimonidine.

      Yohimbe
      Brimonidine
      ×
      1. Berlan M, LeVerge R, Galitzky J, LeCorre P. Alpha 2-adrenoceptor antagonist potencies of two hydroxylated metabolites of yohimbine. Br J Pharmacol 1993;108:927-32.
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

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