Bismuth Subsalicylate
Common brand names:
Kaopectate, Maalox Total Stomach Relief, Pepto-BismolBismuth subsalicylate is a nonprescription drug used to relieve indigestion without constipation, nausea, and abdominal cramps. It is also used to control diarrhea and traveler’s diarrhea. Bismuth subsalicylate is used together with prescription antibiotics and stomach acid-blocking drugs to treat gastric and duodenal ulcers associated with Helicobacter pylori infection.
Summary of Interactions with Vitamins, Herbs, & Foods
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Negative Interactions
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Potential Negative Interaction
Bismuth Subsalicylate
Meadowsweet
Bismuth subsalicylate contains salicylates. Various herbs including meadowsweet (Filipendula ulmaria), poplar (Populus tremuloides),willow (Salix alba), and wintergreen (Gaultheria procumbens) contain salicylates as well. Though similar to aspirin, plant salicylates have been shown to have different actions in test tube studies. Furthermore, salicylates are poorly absorbed and likely do not build up to levels sufficient to cause negative interactions that aspirin might. No reports have been published of negative interactions between salicylate-containing plants and aspirin or aspirin-containing drugs. Therefore concerns about combining salicylate-containing herbs remain theoretical, and the risk of causing problems appears to be low.
MeadowsweetBismuth Subsalicylate- Wichtl M, Bisset NG, eds. Herbal Drugs and Phytopharmaceuticals Stuttgart: Medpharm GmBH Scientific Publishers. 1994.
- Janssen PL, Katan MB, van Staveren WA, et al. Acetylsalicylate and salicylates in foods. Cancer Lett 1997:114(1-2):163-4.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Product Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, 154-5.
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Potential Negative Interaction
Bismuth Subsalicylate
Poplar
Bismuth subsalicylate contains salicylates. Various herbs including meadowsweet (Filipendula ulmaria), poplar (Populus tremuloides),willow (Salix alba), and wintergreen (Gaultheria procumbens) contain salicylates as well. Though similar to aspirin, plant salicylates have been shown to have different actions in test tube studies. Furthermore, salicylates are poorly absorbed and likely do not build up to levels sufficient to cause negative interactions that aspirin might. No reports have been published of negative interactions between salicylate-containing plants and aspirin or aspirin-containing drugs. Therefore concerns about combining salicylate-containing herbs remain theoretical, and the risk of causing problems appears to be low.
PoplarBismuth Subsalicylate- Wichtl M, Bisset NG, eds. Herbal Drugs and Phytopharmaceuticals Stuttgart: Medpharm GmBH Scientific Publishers. 1994.
- Janssen PL, Katan MB, van Staveren WA, et al. Acetylsalicylate and salicylates in foods. Cancer Lett 1997:114(1-2):163-4.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Product Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, 154-5.
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Potential Negative Interaction
Bismuth Subsalicylate
White Willow
Bismuth subsalicylate contains salicylates. Various herbs including meadowsweet (Filipendula ulmaria), poplar (Populus tremuloides),willow (Salix alba), and wintergreen (Gaultheria procumbens) contain salicylates as well. Though similar to aspirin, plant salicylates have been shown to have different actions in test tube studies. Furthermore, salicylates are poorly absorbed and likely do not build up to levels sufficient to cause negative interactions that aspirin might. No reports have been published of negative interactions between salicylate-containing plants and aspirin or aspirin-containing drugs. Therefore concerns about combining salicylate-containing herbs remain theoretical, and the risk of causing problems appears to be low.
White WillowBismuth Subsalicylate- Wichtl M, Bisset NG, eds. Herbal Drugs and Phytopharmaceuticals Stuttgart: Medpharm GmBH Scientific Publishers. 1994.
- Janssen PL, Katan MB, van Staveren WA, et al. Acetylsalicylate and salicylates in foods. Cancer Lett 1997:114(1-2):163-4.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Product Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, 154-5.
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Potential Negative Interaction
Bismuth Subsalicylate
Wintergreen
Bismuth subsalicylate contains salicylates. Various herbs including meadowsweet (Filipendula ulmaria), poplar (Populus tremuloides),willow (Salix alba), and wintergreen (Gaultheria procumbens) contain salicylates as well. Though similar to aspirin, plant salicylates have been shown to have different actions in test tube studies. Furthermore, salicylates are poorly absorbed and likely do not build up to levels sufficient to cause negative interactions that aspirin might. No reports have been published of negative interactions between salicylate-containing plants and aspirin or aspirin-containing drugs. Therefore concerns about combining salicylate-containing herbs remain theoretical, and the risk of causing problems appears to be low.
WintergreenBismuth Subsalicylate- Wichtl M, Bisset NG, eds. Herbal Drugs and Phytopharmaceuticals Stuttgart: Medpharm GmBH Scientific Publishers. 1994.
- Janssen PL, Katan MB, van Staveren WA, et al. Acetylsalicylate and salicylates in foods. Cancer Lett 1997:114(1-2):163-4.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Product Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, 1997, 154-5.
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