Nutritional Supplement

Gamma Oryzanol

Also indexed as: Oryzanol

Possible Deficiencies

Since gamma oryzanol is not an essential nutrient, it is not associated with a deficiency state.

Side Effects

Some research suggests that gamma oryzanol taken in moderately high amounts (up to 600 mg per day) for several months can cause dry mouth, sleepiness, hot flushes, irritability, and light headedness in some individuals.6

References

1. Maruyama K, Kashiwazaki K, Toyama K, Tsuchiya M. Usefulness of Hi-Z fine granule (gamma-Oryzanol) for the treatment of autonomic instability in gastrointestinal system. Shinyaku To Rinsho 1976;25:124 [in Japanese].

2. Takemoto T, Miyoshi H, Nagashima H. Clinical trial of Hi-Z fine granules (gamma-oryzanol) on gastrointestinal symptoms at 375 hospitals (Japan). Shinyaku To Rinsho 1977;26 [in Japanese].

3. Wheeler KB, Garleb KA. Gamma oryzanol-plant sterol supplementation: metabolic, endocrine, and physiologic effects. Int J Sport Nutr 1991;1:170-7 [review].

4. Fry AC, Bonner E, Lewis DL, et al. The effects of gamma-oryzanol supplementation during resistance exercise training. Int J Sport Nutr 1997;7:318-29.

5. Bucci LR, Blackman G, Defoyd W, et al. Effect of ferulate on strength and body composition of weightlifters. J Appl Sport Sci Res 1990;4:110 [abstract].

6. Takemoto T, Miyoshi H, Nagashima H. Clinical trial of Hi-Z fine granules (gamma-oryzanol) on gastrointestinal symptoms at 375 hospitals (Japan). Shinyaku To Rinsho 1977;26 [in Japanese].

Copyright © 2025 TraceGains, Inc. All rights reserved.

Learn more about TraceGains, the company.

The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.