Nutritional Supplement

Corydalis

  • Pain Management

    Pain

    Preliminary reports indicate that THP (an alkaloid from the plant corydalis) may be effective in reducing nerve pain.
    Pain
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    Preliminary reports from Chinese researchers also note that 75 mg per day of THP (an alkaloid from the plant corydalis) was effective in reducing nerve pain in 78% of those tested.9

  • Sleep Support

    Insomnia

    Corydalis contains several ingredients, one of which has been shown to influence the nervous system, providing pain relief and promoting relaxation.
    Insomnia
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    Corydalis contains several ingredients, one of which has been shown to influence the nervous system, providing pain relief and promoting relaxation. People with insomnia were able to fall sleep more easily after taking 100 to 200 mg per day of a corydalis extract (called dl-tetrahydropalmatine, or DHP), according to a preliminary report.10People taking the extract reported no drug hangover symptoms, such as dizziness or vertigo.

  • Menstrual and PMS Support

    Dysmenorrhea

    A constituent of corydalis called tetrahydropalmatine appears to heave pain-relieving and sedative effects. It has shown to be effective for painful menstruation.
    Dysmenorrhea
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    Corydalis contains several alkaloids, and one called tetrahydropalmatine (THP) is considered to be the most potent. In laboratory research, THP has been shown to exhibit a wide number of pharmacological actions on the central nervous system, including pain-relieving and sedative effects.11 According to a secondary reference, painful menstruation responded favorably to the administration of THP.12 For a pain-relieving effect, the recommended amount for the crude dried rhizome is 5–10 grams per day. Alternatively, one can take 10–20 ml per day of a 1:2 extract.

  • Women's Health

    Dysmenorrhea

    A constituent of corydalis called tetrahydropalmatine appears to heave pain-relieving and sedative effects. It has shown to be effective for painful menstruation.
    Dysmenorrhea
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    Corydalis contains several alkaloids, and one called tetrahydropalmatine (THP) is considered to be the most potent. In laboratory research, THP has been shown to exhibit a wide number of pharmacological actions on the central nervous system, including pain-relieving and sedative effects.13 According to a secondary reference, painful menstruation responded favorably to the administration of THP.14 For a pain-relieving effect, the recommended amount for the crude dried rhizome is 5–10 grams per day. Alternatively, one can take 10–20 ml per day of a 1:2 extract.

  • Digestive Support

    Peptic Ulcer

    Corydalis extracts are useful in relieving pain and in treating stomach ulcers.
    Peptic Ulcer
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    Extracts of the herb corydalis are not only helpful as pain-relief agents but also may be useful in the treatment of stomach ulcers. In a study of people with stomach and intestinal ulcers or chronic inflammation of the stomach lining, 90 to 120 mg of corydalis extract per day (equal to 5 to 10 grams of the crude herb) was found to be effective in 76% of the participants.15

  • Heart and Circulatory Health

    Cardiac Arrhythmia

    An active constituent in corydalis, dl-tetrahydropalmatine, may have an anti-arrhythmic effect on the heart.
    Cardiac Arrhythmia
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    An active constituent in corydalis, dl-tetrahydropalmatine (dl-THP), may exert an anti-arrhythmic action on the heart. This action was observed in a preliminary trial with 33 patients suffering from a specific type of arrhythmia called supraventricular premature beat or SVPB.16 Each patient took 300 to 600 mg of dl-THP per day in tablet form, and the dl-THP was found to be significantly more effective than placebo in reducing arrhythmia.

What Are Star Ratings?
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Reliable and relatively consistent scientific data showing a substantial health benefit.
Contradictory, insufficient, or preliminary studies suggesting a health benefit or minimal health benefit.
For an herb, supported by traditional use but minimal or no scientific evidence. For a supplement, little scientific support.

Our proprietary “Star-Rating” system was developed to help you easily understand the amount of scientific support behind each supplement in relation to a specific health condition. While there is no way to predict whether a vitamin, mineral, or herb will successfully treat or prevent associated health conditions, our unique ratings tell you how well these supplements are understood by the medical community, and whether studies have found them to be effective for other people.

For over a decade, our team has combed through thousands of research articles published in reputable journals. To help you make educated decisions, and to better understand controversial or confusing supplements, our medical experts have digested the science into these three easy-to-follow ratings. We hope this provides you with a helpful resource to make informed decisions towards your health and well-being.

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Traditional Use (May Not Be Supported by Scientific Studies)

In Traditional Chinese Medicine, corydalis is said to invigorate the blood, move qi (energy that travels through the body), and alleviate pain, including menstrual, abdominal, and hernial.17

References

1. Zhu YP. Chinese Materia Media: Chemistry, Pharmacology, and Applications. Australia: Harwood Academic Publishers, 1998, 445-8.

2. Hsu HY. Oriental Materia Medica: A Concise Guide. Long Beach, CA: Oriental Healing Arts Institute, 1986, 448-50.

3. Zhu YP. Chinese Materia Media: Chemistry, Pharmacology, and Applications. Australia: Harwood Academic Publishers, 1998, 445-8.

4. Xing JF, Wang MN, Ma XY, et al. Effects of dl-tetrahydropalmatine on rabbit platelet aggregation and experimental thrombosis in rats. Chin Pharm Bull 1997;13:258-60.

5. Lin MT, Chueh FY, Hsieh MT, et al. Antihypertensive effects of dl-tetrahydropalmatine: an active principle isolated from corydalis. Clin Exper Pharm Physiol 1996;23:738-42.

6. Xiaolin N, Zhenhua H, Xin M, et al. Clinical and experimental study of dl-tetrahydropalmatine effect in the treatment of supraventricular arrhythmia. J Xi'An Med Univ 1998;10:150-3.

7. Chang HM, But PPH. Pharmacology and Applications of Chinese Materia Medica vol 1. Singapore: World Scientific Inc., 1986, 521.

8. Lin DZ, Fang YS. Modern Study and Application of Materia Medica. Hong Kong: China Ocean Press, 1990, 323-5.

9. Lin DZ, Fang YS. Modern Study and Application of Materia Medica. Hong Kong: China Ocean Press, 1990, 323-5.

10. Chang HM, But PPH. Pharmacology and Applications of Chinese Materia Medica vol 1. Singapore: World Scientific Inc., 1986, 521.

11. Zhu YP. Chinese Materia Media: Chemistry, Pharmacology, and Applications. Australia: Harwood Academic Publishers, 1998, 445-8.

12. Zhu YP. Chinese Materia Medica: Chemistry, Pharmacology, and Applications. Australia: Harwood Academic Publishers, 1998, 445-8

13. Zhu YP. Chinese Materia Media: Chemistry, Pharmacology, and Applications. Australia: Harwood Academic Publishers, 1998, 445-8.

14. Zhu YP. Chinese Materia Medica: Chemistry, Pharmacology, and Applications. Australia: Harwood Academic Publishers, 1998, 445-8

15. Chang HM, But PPH. Pharmacology and Applications of Chinese Materia Medica vol 1. Singapore: World Scientific Inc., 1986, 521.

16. Xiaolin N, Zhenhua H, Xin M, et al. Clinical and experimental study of dl-tetrahydropalmatine effect in the treatment of supraventricular arrhythmia. J Xi'An Med Univ 1998;10:150-3.

17. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Vista, CA: Eastland Press, 1993, 270.

18. Bone K. Clinical Applications of Ayurvedic and Chinese Herbs. Warwick, Queensland, Australia: Phytotherapy Press, 1996, 25-8.

19. Bensky D, Gamble A, Kaptchuk T. Chinese Herbal Medicine Materia Medica. Vista, CA: Eastland Press, 1993, 270.

20. Horowitz RS, Feldhaus K, Dart RC, et al. The clinical spectrum of Jin Bu Huan toxicity. Arch Int Med 1996;156:899-903.

21. Kaptchuk TJ, Woolf GM, Vierling JM. Acute hepatitis associated with Jin Bu Huan. Ann Int Med 1995;122:636.

22. Anonymous. Jin Bu Huan toxicity in adults—Los Angeles, 1993. JAMA 1994;271:423-4.

23. Chang HM, But PPH. Pharmacology and Applications of Chinese Materia Medica vol 1. Singapore: World Scientific Inc., 1986, 521.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.