Nutritional Supplement

Asian Ginseng

Parts Used & Where Grown

Asian ginseng is a member of the Araliaceae family, which also includes the closely related American ginseng (Panax quinquefolius) and less similar Siberian ginseng (Eleutherococcus senticosus), also known as eleuthero. Asian ginseng commonly grows on mountain slopes and is usually harvested in the fall. The root is used, preferably from plants older than six years of age.

How It Works

Ginseng’s actions in the body are thought to be due to a complex interplay of constituents. The primary group are the ginsenosides, which are believed to counter the effects of stress and enhance intellectual and physical performance. Thirteen ginsenosides have been identified in Asian ginseng. Two of them, ginsenosides Rg1 and Rb1, have been closely studied.1 Other constituents include the panaxans, which may help lower blood sugar, and the polysaccharides (complex sugar molecules), which are thought to support immune function.2,3

Long-term intake of Asian ginseng may be linked to a reduced risk of some forms of cancer.4,5 A double-blind trial found that 200 mg of Asian ginseng per day improved blood sugar levels in people with type 2 (non-insulin-dependent) diabetes.6 Human trials have mostly failed to confirm the purported benefit of Asian ginseng for the enhancement of athletic performance.7,8 One preliminary trial suggests it may help those in poor physical condition to tolerate exercise better.9 In combination with some vitamins and minerals, 80 mg of ginseng per day was found to effectively reduce fatigue in a double-blind trial.10 Another double-blind trial also found it helpful for relief of fatigue and, possibly, stress.11 Although there are no human clinical trials, adaptogenic herbs such as Asian ginseng may be useful for people with chronic fatigue syndrome. This may be because these herbs are thought to have an immuno-modulating effect and also help support the normal function of the hypothalamic-pituitary-adrenal axis, the hormonal stress system of the body.12

Asian ginseng may also prove useful for male infertility. A double-blind trial with a large group of infertile men found that 4 grams of Asian ginseng per day for three months led to an improvement in sperm count and sperm motility.13

Asian ginseng may also help men with erectile dysfunction. A double-blind trial in Korea found that 1,800 mg per day of Asian ginseng extract for three months helped improve libido and the ability to maintain an erection in men with erectile dysfunction.14 This finding was confirmed in another double-blind study, in which 900 mg three times a day was given for eight weeks.15

References

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2. Tomoda M, Hirabayashi K, Shimizu N, et al. Characterization of two novel polysaccharides having immunological activities from the root of Panax ginseng. Biol Pharm Bull 1993;16:1087-90.

3. See DM, Broumand N, Sahl L, Tilles JG. In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients. Immunopharmacology 1997;35:229-35.

4. Yun TK, Choi Y. Non-organ specific cancer prevention of ginseng: A prospective study in Korea. Int J Epidemiol 1998;27:359-64.

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6. Sotaniemi EA, Haapakoski E, Rautio A. Ginseng therapy in non-insulin-dependent diabetic patients. Diabetes Care 1995;18:1373-5.

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8. Allen JD, McLung J, Nelson AG, Welsch M. Ginseng supplementation does not enhance healthy young adults' peak aerobic exercise performance. J Am Coll Nutr 1998;17:462-6.

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11. Caso Mardsco A, Vargas Ruiz R, Salas Villagomez A, Begona Infante C. Double-blind study of a multivitamin complex supplemented with ginseng extract. Drugs Exp Clin Res 1996;22:323-9.

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20. Hong B, Ji YH, Hong JH, et al. A double-blind crossover study evaluating the efficacy of Korean red ginseng in patients with erectile dysfunction: a preliminary report. J Urol 2002;168:2070-3.

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34. Neri M, Andermarcher E, Pradelli JM, Salvioli G. Influence of a double blind pharmacological trial on two domains of well-being in subjects with age associated memory impairment. Arch Gerontol Geriatr 1995;21:241-52.

35. Hallstrom C, Fulder S, Carruthers M. Effect of ginseng on the performance of nurses on night duty. Comp Med East West 1982;6:277-82.

36. Sotaniemi EA, Haapakoski E, Rautio A. Ginseng therapy in non-insulin-dependent diabetic patients. Diabetes Care 1995;18:1373-5.

37. Caso Mardsco A, Vargas Ruiz R, Salas Villagomez A, Begona Infante C. Double-blind study of a multivitamin complex supplemented with ginseng extract. Drugs Exp Clin Res 1996;22:323-9.

38. Wesnes KA, Luthringer R, Ambrosetti L, et al. The effects of a combination of Panax ginseng, vitamins and minerals on mental performance, mood and physical fatigue in nurses working night shifts: a double-blind, placebo controlled trial. Curr Top Nutraceut Res 2003;1:169-76.

39. Cardinal BJ, Engels HJ. Ginseng does not enhance psychological well-being in healthy, young adults: results of a double-blind, placebo-controlled, randomized clinical trial. J Am Diet Assoc 2001;101:655-60.

40. Gui Q, Xu Z, Xu K, Yang Y. The Efficacy of Ginseng-Related Therapies in Type 2 Diabetes Mellitus: An Updated Systematic Review and Meta-analysis. Medicine (Baltimore) 2016;95:e2584.

41. Shishtar E, Sievenpiper J, Djedovic V, et al. The effect of ginseng (the genus panax) on glycemic control: a systematic review and meta-analysis of randomized controlled clinical trials. PLoS One 2014;9:e107391.

42. Oh M, Park S, Kim S, et al. Postprandial glucose-lowering effects of fermented red ginseng in subjects with impaired fasting glucose or type 2 diabetes: a randomized, double-blind, placebo-controlled clinical trial. BMC Complement Altern Med 2014;14:237.

43. Zhou P, Xie W, He S, et al. Ginsenoside Rb1 as an Anti-Diabetic Agent and Its Underlying Mechanism Analysis. Cells 2019;8.

44. Bai L, Gao J, Wei F, et al. Therapeutic Potential of Ginsenosides as an Adjuvant Treatment for Diabetes. Front Pharmacol 2018;9:423.

45. Bang H, Kwak JH, Ahn HY, et al. Korean red ginseng improves glucose control in subjects with impaired fasting glucose, impaired glucose tolerance, or newly diagnosed type 2 diabetes mellitus. J Med Food 2014;17:128–34.

46. Yoon J, Kang S, Vassy J, et al. Efficacy and safety of ginsam, a vinegar extract from Panax ginseng, in type 2 diabetic patients: Results of a double-blind, placebo-controlled study. J Diabetes Investig 2012;3:309–17.

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49. Bai L, Gao J, Wei F, et al. Therapeutic Potential of Ginsenosides as an Adjuvant Treatment for Diabetes. Front Pharmacol 2018;9:423.

50. Wiklund IK, Mattson LA, Lindgren R, et al. Effects of a standardized ginseng extract on quality of life and psychological parameters in symptomatic postmenopausal women: a double-blind, placebo-controlled trial. Int J Clin Pharm Res 1999;19:89-99.

51. Kim SY, Seo SK, Choi YM, et al. Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind randomized controlled trial. Menopause 2012;19:461-6.

52. Wiklund IK, Mattson LA, Lindgren R, et al. Effects of a standardized ginseng extract on quality of life and psychological parameters in symptomatic postmenopausal women: a double-blind, placebo-controlled trial. Int J Clin Pharm Res 1999;19:89-99.

53. Kim SY, Seo SK, Choi YM, et al. Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind randomized controlled trial. Menopause 2012;19:461-6.

54. Lee ST, Chu K, Sim JY, et al. Panax ginseng enhances cognitive performance in Alzheimer disease. Alzheimer Dis Assoc Disord 2008;22:222-6.

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62. Engels HJ, Kolokouri I, Cieslak TJ 2nd, Wirth JC. Effects of ginseng supplementation on supramaximal exercise performance and short-term recovery. J Strength Cond Res 2001;15:290-5.

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The information presented by TraceGains is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over the counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2025.