Drug

Zolmitriptan

Common brand names:

Zomig, Zomig ZMT

Zolmitriptan is used to treat acute attacks of migraine headache and is in a class of drugs known as serotonin antagonists.

Summary of Interactions with Vitamins, Herbs, & Foods

  • Negative Interactions

    1

    • Zolmitriptan

      L-Tryptophan

      Potential Negative Interaction

      Zolmitriptan works by stimulating serotonin receptors in the brain. 5-HTP (5-Hydroxytryptophan) and L-tryptophan are converted to serotonin in the brain, and taking them with zolmitriptan could increase zolmitriptan-induced side effects. However, no interactions have yet been reported with zolmitriptan and 5-HTP or L-tryptophan.

  • Explanation Required

    1

    • Zolmitriptan

      5-HTP

      Needs Explanation

      Zolmitriptan works by stimulating serotonin receptors in the brain. 5-HTP (5-Hydroxytryptophan) and L-tryptophan are converted to serotonin in the brain, and taking them with zolmitriptan could increase zolmitriptan-induced side effects. However, no interactions have yet been reported with zolmitriptan and 5-HTP or L-tryptophan.

The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

Copyright © 2025 TraceGains, Inc. All rights reserved.

RxAnswers™ is a copyrighted product from TraceGains.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

There are some limitations on the information provided in “Nutrient Interactions.” Do NOT rely solely on the information in this article. Please read the disclaimer.

Learn more about TraceGains, the company.

Learn more about the authors of RxAnswers.

TraceGains and/or its suppliers make no warranties or representations as to the accuracy or completeness of this content herein or that of any organization referred or linked to within this content and will not be liable for any damages arising out of your access to or use of any information found herein or that of any organization referred to within this content.

Information expires December 2025.