Drug

Magnesium Hydroxide

Common brand names:

Phillips Milk of Magnesia

Magnesium hydroxide is used as an antacid for short-term relief of stomach upset and as a laxative for short-term treatment of constipation. Magnesium hydroxide is available in nonprescription products alone and in combination with other nonprescription ingredients to relieve stomach upset.

Summary of Interactions with Vitamins, Herbs, & Foods

  • Supportive Interactions

    2
    • Magnesium Hydroxide

      Folic Acid

      Replenish Depleted Nutrients

      Folic acid is needed by the body to utilize vitamin B12. Antacids, including magnesium hydroxide, inhibit folic acid absorption. People taking antacids are advised to supplement with folic acid.

      Folic Acid
      Magnesium Hydroxide
      ×
      1. Russell RM, Golner BB, Krasinski SD, et al. Effect of antacid and H2 receptor antagonists on the intestinal absorption of folic acid. J Lab Clin Med 1988;112:458-63.
    • Magnesium Hydroxide

      Iron

      Replenish Depleted Nutrients

      Antacids, including magnesium hydroxide, may reduce the absorption of dietary iron. Iron supplements do not require stomach acid for absorption and one human study found that a magnesium hydroxide/aluminum hydroxide antacid did not decrease supplemental iron absorption.

      Iron
      Magnesium Hydroxide
      ×
      1. O'Neil-Cutting MA, Crosby WH. The effect of antacids on the absorption of simultaneously ingested iron. JAMA 1986;255:1468-70.
  • Explanation Required

    1
    • Magnesium Hydroxide

      Potassium

      Needs Explanation

      Individuals taking potassium-depleting diuretics and those who are otherwise at risk of developing potassium deficiency (such as people with chronic diarrhea or vomiting) may experience a fall in serum potassium levels if they take magnesium without taking additional potassium. This could lead to muscle cramps or, in individuals taking digoxin or digitalis, more serious problems such as cardiac arrhythmias. Individuals who have a history of potassium deficiency and those who are at risk of developing potassium deficiency, as well as people taking digoxin or digitalis, should consult a physician before taking magnesium-containing products.

      Potassium
      Magnesium Hydroxide
      ×
      1. Dyckner T, Wester PO. Ventricular extrasystoles and intracellular electrolytes before and after potassium and magnesium infusions in patients on diuretic treatment. Am Heart J 1979;97:12-8.
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

Copyright © 2024 TraceGains, Inc. All rights reserved.

RxAnswers™ is a copyrighted product from TraceGains.

This information is intended only for residents of the United States. Products sold under the same brand names in other countries may contain different ingredients.

There are some limitations on the information provided in “Nutrient Interactions.” Do NOT rely solely on the information in this article. Please read the disclaimer.

Learn more about TraceGains, the company.

Learn more about the authors of RxAnswers.

TraceGains and/or its suppliers make no warranties or representations as to the accuracy or completeness of this content herein or that of any organization referred or linked to within this content and will not be liable for any damages arising out of your access to or use of any information found herein or that of any organization referred to within this content.

Information expires December 2024.