Drug

Diltiazem

Common brand names:

Cardizem CD, DilacorXR, Tiazac, Cardizem LA, Dilt CD, Dilt XR

Diltiazem is a calcium channel blocker used to treat angina pectoris, heart arrhythmias, and high blood pressure.

Summary of Interactions with Vitamins, Herbs, & Foods

  • Negative Interactions

    1

    • Diltiazem

      DHEA

      Reduces Effectiveness

      Diltiazem has been shown to raise blood levels of DHEA and DHEA-sulfate in insulin-resistant, obese men with high blood pressure.

      DHEA
      Diltiazem
      ×
      1. Beer NA, Jakubowicz DJ, Beer RM, Nestler JE. Disparate effects of insulin reduction with diltiazem on serum dehydroepiandrosterone sulfate levels in obese hypertensive men and women. J Clin Endocrinol Metab 1994;79:1077-81.

  • Explanation Required

    1

    • Diltiazem

      Pleurisy Root

      Needs Explanation

      As pleurisy root and other plants in the Aesclepius genus contain cardiac glycosides, it is best to avoid use of pleurisy root with heart medications such as calcium channel blockers.

      Pleurisy Root
      Diltiazem
      ×
      1. Newall CA, Anderson LA, Phillipson JD. Herbal Medicines: A Guide for Health-Care Professionals. London: Pharmaceutical Press, 1996, 213-4.
The Drug-Nutrient Interactions table may not include every possible interaction. Taking medicines with meals, on an empty stomach, or with alcohol may influence their effects. For details, refer to the manufacturers’ package information as these are not covered in this table. If you take medications, always discuss the potential risks and benefits of adding a new supplement with your doctor or pharmacist.

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